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Epigenetic silencing of the tumor suppressor TIMP-3 gene in upstream CpG islands in thyroid neoplasms: a cross-sectional study with systematic review.

메타분석 1/5 보강

Molecular biology reports 📖 저널 OA 12.1% 2022~2026 2025 Vol.52(1) p. 665

PICO 자동 추출 (휴리스틱, conf 2/4)

유사 논문

P · Population 대상 환자/모집단

64 patients were analyzed, including 28 with PTC, 9 with FTC, and 27 with benign thyroid nodules.

I · Intervention 중재 / 시술

추출되지 않음

C · Comparison 대조 / 비교

추출되지 않음

O · Outcome 결과 / 결론

[CONCLUSION] Changes in the methylation pattern of the TIMP-3 promoter could help distinguish between benign and malignant thyroid nodules. These changes could be explored as targets for demethylation interventions, potentially opening new avenues for treatments aimed at restoring normal methylation patterns and influencing thyroid nodule behavior.

Zarkesh M, Arab N, Abooshahab R, Heydarzadeh S, Nozhat Z, Jahromi MS

PubMed ↗ DOI ↗ BibTeX ↓ RIS ↓

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