Adjuvant External Beam Radiotherapy in Differentiated Thyroid Cancers: An Audit of Clinical Practice, Adapting to New Evidence.
1/5 보강
PICO 자동 추출 (휴리스틱, conf 2/4)
유사 논문P · Population 대상 환자/모집단
환자: DTC treated with adjuvant Intensity Modulated radiotherapy (IMRT) from 2011 to 2024
I · Intervention 중재 / 시술
추출되지 않음
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
Late toxicity, including tracheostomy placement and feeding tube dependence, was seen in three and one patient, respectively. [CONCLUSION] Adjuvant IMRT in patients with DTC with high risk of locoregional recurrence resulted in good LRC with acceptable toxicities.
[INTRODUCTION] There is limited evidence on the role of adjuvant external beam radiotherapy in differentiated thyroid cancer (DTC).
- 추적기간 53 months
APA
Laskar SG, Mohanty S, et al. (2025). Adjuvant External Beam Radiotherapy in Differentiated Thyroid Cancers: An Audit of Clinical Practice, Adapting to New Evidence.. Head & neck, 47(12), 3285-3293. https://doi.org/10.1002/hed.28222
MLA
Laskar SG, et al.. "Adjuvant External Beam Radiotherapy in Differentiated Thyroid Cancers: An Audit of Clinical Practice, Adapting to New Evidence.." Head & neck, vol. 47, no. 12, 2025, pp. 3285-3293.
PMID
40662300 ↗
Abstract 한글 요약
[INTRODUCTION] There is limited evidence on the role of adjuvant external beam radiotherapy in differentiated thyroid cancer (DTC).
[METHODS] We conducted a retrospective study of patients with DTC treated with adjuvant Intensity Modulated radiotherapy (IMRT) from 2011 to 2024.
[RESULTS] Fifty-nine patients were analyzed with median follow-up of 53 months. All the patients had undergone total thyroidectomy. Gross extrathyroidal extension was seen in 76% of patients, while 54% had R1/R2 resection. High-risk histological types were seen in 51% of patients, while 34% had recurrent disease. The 5-year locoregional control (LRC) was 89.3% while 5-year overall survival (OS) was 84.6%. Acute Grade 3 dermatitis and dysphagia were seen in 12% and 10%, respectively. Late toxicity, including tracheostomy placement and feeding tube dependence, was seen in three and one patient, respectively.
[CONCLUSION] Adjuvant IMRT in patients with DTC with high risk of locoregional recurrence resulted in good LRC with acceptable toxicities.
[METHODS] We conducted a retrospective study of patients with DTC treated with adjuvant Intensity Modulated radiotherapy (IMRT) from 2011 to 2024.
[RESULTS] Fifty-nine patients were analyzed with median follow-up of 53 months. All the patients had undergone total thyroidectomy. Gross extrathyroidal extension was seen in 76% of patients, while 54% had R1/R2 resection. High-risk histological types were seen in 51% of patients, while 34% had recurrent disease. The 5-year locoregional control (LRC) was 89.3% while 5-year overall survival (OS) was 84.6%. Acute Grade 3 dermatitis and dysphagia were seen in 12% and 10%, respectively. Late toxicity, including tracheostomy placement and feeding tube dependence, was seen in three and one patient, respectively.
[CONCLUSION] Adjuvant IMRT in patients with DTC with high risk of locoregional recurrence resulted in good LRC with acceptable toxicities.
🏷️ 키워드 / MeSH 📖 같은 키워드 OA만
- Humans
- Thyroid Neoplasms
- Male
- Female
- Retrospective Studies
- Middle Aged
- Radiotherapy
- Adjuvant
- Adult
- Aged
- Intensity-Modulated
- Thyroidectomy
- Neoplasm Recurrence
- Local
- Treatment Outcome
- Young Adult
- Follow-Up Studies
- adjuvant external beam radiotherapy
- differentiated thyroid cancer
- intensity‐modulated radiation therapy
🏷️ 같은 키워드 · 무료전문 — 이 논문 MeSH/keyword 기반
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