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Single-cell RNA sequencing reveals tumor cell and immune cell variations associated with lymphatic metastasis in papillary thyroid cancer.

1/5 보강
Endocrine connections 📖 저널 OA 100% 2022: 6/6 OA 2023: 8/8 OA 2024: 12/12 OA 2025: 11/11 OA 2026: 9/9 OA 2022~2026 2025 Vol.14(12)
Retraction 확인
출처

PICO 자동 추출 (휴리스틱, conf 2/4)

유사 논문
P · Population 대상 환자/모집단
환자: PTC were used for viable cell single-cell RNA sequencing (scRNA-seq) analysis
I · Intervention 중재 / 시술
추출되지 않음
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
Specifically, CD8+ resident memory T cells emerged as pivotal regulators in LM of PTC, primarily through the expression of MHC-I, CD99, and LCK. [CONCLUSIONS] This study provides new insights into the heterogeneity of PTC and the basis for LM in PTC, which might provide potential therapeutic targets in future treatment.

Chen Y, Zhao J, Sun Y, Yang Z, Yang C, Zhu D


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