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Follicular Thyroid Carcinoma Metastasis to the Retromolar Trigone: A Case Report.

Cureus 2026 Vol.18(2) p. e103245

Almutairy HM, Alshurafa H, Alsaedi M, Albarrak YM, Alahmadi RM, AlGhamdi FR, Al Mutairy AS, Alkhalifah YA

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Follicular thyroid carcinoma (FTC) may occasionally present with metastatic disease at atypical oral sites.

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APA Almutairy HM, Alshurafa H, et al. (2026). Follicular Thyroid Carcinoma Metastasis to the Retromolar Trigone: A Case Report.. Cureus, 18(2), e103245. https://doi.org/10.7759/cureus.103245
MLA Almutairy HM, et al.. "Follicular Thyroid Carcinoma Metastasis to the Retromolar Trigone: A Case Report.." Cureus, vol. 18, no. 2, 2026, pp. e103245.
PMID 41822648

Abstract

Follicular thyroid carcinoma (FTC) may occasionally present with metastatic disease at atypical oral sites. This report describes a case of FTC involving the retromolar trigone. A 48-year-old woman with a history of FTC treated a decade earlier with total thyroidectomy and radioactive iodine therapy presented with a two-month history of a mass in the left retromolar region. Histopathological analysis of an incisional biopsy confirmed a metastatic well-differentiated follicular thyroid carcinoma. A conservative surgical approach involving left-sided modified radical neck dissection, followed by radioactive iodine management, caused complete resolution of the patient's retromolar lesion. Follow-up over six months showed no evidence of recurrence. This case highlights a rare presentation of FTC metastasizing to the retromolar trigone. It underscores the importance of maintaining a high index of suspicion for metastatic disease in unusual oral lesions in patients with a history of thyroid cancer.