Anterior Skull Base Metastasis From Papillary Thyroid Carcinoma: A Case Report.
증례보고
1/5 보강
PICO 자동 추출 (휴리스틱, conf 3/4)
유사 논문P · Population 대상 환자/모집단
환자: papillary thyroid carcinoma (PTC) and most commonly involves the lungs and bones, with skull base involvement being exceedingly rare
I · Intervention 중재 / 시술
endoscopic surgical debulking followed by postoperative radiation therapy
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
Management required recognition of this diagnostic challenge and combined endoscopic resection and stereotactic radiotherapy, achieving local control while preserving neurologic function. The patient has remained stable at 7-month follow-up.
Distant metastasis occurs in 1% to 4% of patients with papillary thyroid carcinoma (PTC) and most commonly involves the lungs and bones, with skull base involvement being exceedingly rare.
APA
Thapa M, Fischer JL, et al. (2026). Anterior Skull Base Metastasis From Papillary Thyroid Carcinoma: A Case Report.. Ear, nose, & throat journal, 1455613261428524. https://doi.org/10.1177/01455613261428524
MLA
Thapa M, et al.. "Anterior Skull Base Metastasis From Papillary Thyroid Carcinoma: A Case Report.." Ear, nose, & throat journal, 2026, pp. 1455613261428524.
PMID
41824362 ↗
Abstract 한글 요약
Distant metastasis occurs in 1% to 4% of patients with papillary thyroid carcinoma (PTC) and most commonly involves the lungs and bones, with skull base involvement being exceedingly rare. We present a case of a 58-year-old male patient who experienced skull-base metastasis of tall-cell variant PTC 4 years after multimodal treatment of aggressive disease. The patient presented to the otolaryngology clinic with left-sided postnasal drip, anosmia, ptosis, and proptosis. Magnetic resonance imaging of head showed a 1.9 × 2.7 × 4.4 cm mass with extensive invasion of the sinonasal cavities, cribriform plate, and left orbit, complicated by a postobstructive mucocele. In-office biopsy was consistent with metastatic PTC. He underwent endoscopic surgical debulking followed by postoperative radiation therapy. This case demonstrates how PTC with aggressive features can develop anterior skull base metastases years after initial treatment. Management required recognition of this diagnostic challenge and combined endoscopic resection and stereotactic radiotherapy, achieving local control while preserving neurologic function. The patient has remained stable at 7-month follow-up.
🏷️ 키워드 / MeSH 📖 같은 키워드 OA만
🏷️ 같은 키워드 · 무료전문 — 이 논문 MeSH/keyword 기반
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