State-of-the-art application of nanoparticles in radiotherapy: a platform for synergistic effects in cancer treatment.
리뷰
1/5 보강
Radiotherapy (RT) is a gold standard cancer treatment worldwide.
APA
Mostafavi M, Ghazi F, et al. (2025). State-of-the-art application of nanoparticles in radiotherapy: a platform for synergistic effects in cancer treatment.. Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 201(6), 577-588. https://doi.org/10.1007/s00066-024-02301-y
MLA
Mostafavi M, et al.. "State-of-the-art application of nanoparticles in radiotherapy: a platform for synergistic effects in cancer treatment.." Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], vol. 201, no. 6, 2025, pp. 577-588.
PMID
39367110 ↗
Abstract 한글 요약
Radiotherapy (RT) is a gold standard cancer treatment worldwide. However, RT has limitations and many side effects. Nanoparticles (NPs) have exclusive properties that allow them to be used in cancer therapy. Consequently, the combination of NP and RT opens up a new frontier in cancer treatment. Among NPs, gold nanoparticles (GNPs) are the most extensively studied and are considered ideal radiosensitizers for radiotherapy due to their unique physicochemical properties and high X‑ray absorption. This review analyzes the various roles of NPs as radiosensitizers in radiotherapy of glioblastoma (GBS), prostate cancer, and breast cancer and summarizes recent advances. Furthermore, the underlying mechanisms of NP radiosensitization, including physical, chemical, and biological mechanisms, are discussed, which may provide new directions for next-generation GNP optimization and clinical transformation.
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