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Investigation of binding mechanisms between bovine serum albumin and flutamide using multispectral techniques and molecular dynamics simulations.

1/5 보강

Bioorganic chemistry 📖 저널 OA 2.3% 2024~2026 2025 Vol.160() p. 108479

PICO 자동 추출 (휴리스틱, conf 2/4)

P · Population 대상 환자/모집단

Fluorescence quenching experiments revealed that the intrinsic fluorescence of BSA was reduced by the addition of flutamide through a static quenching mechanism.

I · Intervention 중재 / 시술

추출되지 않음

C · Comparison 대조 / 비교

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O · Outcome 결과 / 결론

MD simulations demonstrated that the BSA-Flutamide complex remained stable throughout the 100 ns simulation without significant structural deviations. This comprehensive analysis provides valuable reference material for understanding the interaction between flutamide and BSA during blood transport.

Li N, Bian C, Guo J, Gao Y, Hu Q, Yang Z

PubMed ↗ DOI ↗ BibTeX ↓ RIS ↓

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