Dietary Fiber Intake and Prostate Cancer Outcomes and All-Cause Mortality: Findings From a Secondary Analysis of the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Study.
1/5 보강
PICO 자동 추출 (휴리스틱, conf 2/4)
유사 논문P · Population 대상 환자/모집단
476 participants (annual screening arm: 25 669 men; usual care arm: 23 807 men) aged 55 to 74 years were enrolled from the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Study between the years 1993 and 2001.
I · Intervention 중재 / 시술
추출되지 않음
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
[CONCLUSIONS] High dietary fiber intake (total, soluble, and insoluble) was found to be associated with decreased all-cause mortality, which may suggest a protective effect of dietary fiber intake. Further prospective studies are needed to build on these findings.
[BACKGROUND] Prostate cancer is one of the most common cancers in the United States.
- p-value P < .01
- 95% CI 0.76 to 0.99
APA
Yang Y, Wang Y, et al. (2025). Dietary Fiber Intake and Prostate Cancer Outcomes and All-Cause Mortality: Findings From a Secondary Analysis of the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Study.. Journal of the Academy of Nutrition and Dietetics, 125(11), 1718-1729. https://doi.org/10.1016/j.jand.2025.07.003
MLA
Yang Y, et al.. "Dietary Fiber Intake and Prostate Cancer Outcomes and All-Cause Mortality: Findings From a Secondary Analysis of the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Study.." Journal of the Academy of Nutrition and Dietetics, vol. 125, no. 11, 2025, pp. 1718-1729.
PMID
40684909 ↗
Abstract 한글 요약
[BACKGROUND] Prostate cancer is one of the most common cancers in the United States. Dietary fiber intake may play a role in reducing cancer risk and mortality. However, the relationship between dietary fiber intake and both prostate cancer risk and prostate cancer-specific mortality remains uncertain.
[OBJECTIVE] The aim of the study was to examine the association between dietary fiber intake and prostate cancer risk, prostate cancer-specific mortality, and all-cause mortality.
[DESIGN] This study was a secondary analysis of the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Study, a multicenter randomized trial conducted in the United States that included 2 arms: one undergoing annual screening and the other receiving usual care.
[PARTICIPANTS/SETTING] A total of 49 476 participants (annual screening arm: 25 669 men; usual care arm: 23 807 men) aged 55 to 74 years were enrolled from the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Study between the years 1993 and 2001.
[MAIN OUTCOME MEASURES] Prostate cancer risk, prostate cancer-specific mortality, and all-cause mortality were considered as main outcomes.
[STATISTICAL ANALYSIS PERFORMED] Cox proportional hazard and competing risk regressions were used within each arm to examine the associations of dietary fiber intake with prostate cancer risk, all-cause mortality, and prostate cancer-specific mortality.
[RESULTS] Compared with the low tertile total fiber intake, high tertile total fiber intake in the annual screening arm was linked to reduced prostate cancer risk (adjusted hazard ratio 0.87; 95% CI, 0.76 to 0.99), and high-soluble fiber intake in the usual care arm had a similar association (adjusted hazard ratio 0.86; 95% CI, 0.75 to 0.98) after adjusting for confounders. There were statistically significant inverse associations between dietary fiber intake (total, insoluble, and soluble) and all-cause mortality among participants in both arms (P < .01). Significant associations of dietary fiber intake (total, soluble, and insoluble) with advanced prostate cancer risk and prostate cancer-specific mortality in both arms were not observed (P > .05).
[CONCLUSIONS] High dietary fiber intake (total, soluble, and insoluble) was found to be associated with decreased all-cause mortality, which may suggest a protective effect of dietary fiber intake. Further prospective studies are needed to build on these findings.
[OBJECTIVE] The aim of the study was to examine the association between dietary fiber intake and prostate cancer risk, prostate cancer-specific mortality, and all-cause mortality.
[DESIGN] This study was a secondary analysis of the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Study, a multicenter randomized trial conducted in the United States that included 2 arms: one undergoing annual screening and the other receiving usual care.
[PARTICIPANTS/SETTING] A total of 49 476 participants (annual screening arm: 25 669 men; usual care arm: 23 807 men) aged 55 to 74 years were enrolled from the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Study between the years 1993 and 2001.
[MAIN OUTCOME MEASURES] Prostate cancer risk, prostate cancer-specific mortality, and all-cause mortality were considered as main outcomes.
[STATISTICAL ANALYSIS PERFORMED] Cox proportional hazard and competing risk regressions were used within each arm to examine the associations of dietary fiber intake with prostate cancer risk, all-cause mortality, and prostate cancer-specific mortality.
[RESULTS] Compared with the low tertile total fiber intake, high tertile total fiber intake in the annual screening arm was linked to reduced prostate cancer risk (adjusted hazard ratio 0.87; 95% CI, 0.76 to 0.99), and high-soluble fiber intake in the usual care arm had a similar association (adjusted hazard ratio 0.86; 95% CI, 0.75 to 0.98) after adjusting for confounders. There were statistically significant inverse associations between dietary fiber intake (total, insoluble, and soluble) and all-cause mortality among participants in both arms (P < .01). Significant associations of dietary fiber intake (total, soluble, and insoluble) with advanced prostate cancer risk and prostate cancer-specific mortality in both arms were not observed (P > .05).
[CONCLUSIONS] High dietary fiber intake (total, soluble, and insoluble) was found to be associated with decreased all-cause mortality, which may suggest a protective effect of dietary fiber intake. Further prospective studies are needed to build on these findings.
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