Postfixation of cryostat sections improves tumor definition in Mohs surgery.
【연구 목적】 모스 미세절제 수술(Mohs micrographic surgery)의 성공은 종양의 정확한 식별과 국소화에 달려 있으며, 본 연구는 냉동 절편(cryostat section)을 포름알데히드(formalin)로 고정하는 후고정(postfixation) 기법이 종양의 정의와 염색 특성을 개선하는지 검증하고자 하였다.
APA
Rustad OJ, Kaye V, et al. (1989). Postfixation of cryostat sections improves tumor definition in Mohs surgery.. The Journal of dermatologic surgery and oncology, 15(12), 1262-7. https://doi.org/10.1111/j.1524-4725.1989.tb03145.x
MLA
Rustad OJ, et al.. "Postfixation of cryostat sections improves tumor definition in Mohs surgery.." The Journal of dermatologic surgery and oncology, vol. 15, no. 12, 1989, pp. 1262-7.
PMID
2480374
Abstract
Precise identification and localization of tumor is the key to success in Mohs micrographic surgery. In a pilot study, we demonstrated improvement in tumor definition and staining characteristics after formalin fixation of cryostat sections (postfixation) when compared with unfixed specimens. We further investigated the benefits of postfixation with a series of tissue fixatives and with varying fixation times. In all cases, postfixation was found to be beneficial. No improvement was noted by extending the postfixation time beyond 1 minute.
추출된 의학 개체 (NER)
| 유형 | 영어 표현 | 한국어 / 풀이 | UMLS CUI | 출처 | 등장 |
|---|---|---|---|---|---|
| 해부 | unfixed
|
scispacy | 1 | ||
| 해부 | tissue
|
scispacy | 1 | ||
| 질환 | tumor
|
C0027651
Neoplasms
|
scispacy | 1 | |
| 질환 | Mohs
|
scispacy | 1 | ||
| 질환 | Mohs micrographic
|
scispacy | 1 |
MeSH Terms
Acetates; Basal Cell Carcinoma; Carcinoma, Squamous Cell; Ethanol; Fixatives; Formaldehyde; Frozen Sections; Histological Techniques; Humans; Microsurgery; Microtomy; Pilot Projects; Single-Blind Method; Skin Neoplasms; Staining and Labeling; Surgery, Plastic