A lateral flow immunoassay strip employing upconversion luminescence for quantitative detection of prostate-specific antigen.
1/5 보강
A highly sensitive immunochromatographic test strip has been developed based on upconversion nanoparticles (UCNPs) for the quantitative detection of prostate-specific antigen (PSA).
APA
Yuan X, Tang Z, et al. (2026). A lateral flow immunoassay strip employing upconversion luminescence for quantitative detection of prostate-specific antigen.. Mikrochimica acta, 193(2), 105. https://doi.org/10.1007/s00604-025-07736-3
MLA
Yuan X, et al.. "A lateral flow immunoassay strip employing upconversion luminescence for quantitative detection of prostate-specific antigen.." Mikrochimica acta, vol. 193, no. 2, 2026, pp. 105.
PMID
41575589
Abstract
A highly sensitive immunochromatographic test strip has been developed based on upconversion nanoparticles (UCNPs) for the quantitative detection of prostate-specific antigen (PSA). UCNPs exhibit distinctive anti-Stokes luminescence properties, enabling near-infrared excitation with visible light emission, which significantly reduces background autoluminescence and enhances signal clarity. The fabricated test strip demonstrated excellent sensitivity, specificity, and reproducibility in PSA detection, offering a promising platform for rapid, point-of-care testing. This approach holds potential for improving prostate cancer screening and real-time disease management in clinical and resource-limited settings.
MeSH Terms
Prostate-Specific Antigen; Humans; Immunoassay; Male; Reagent Strips; Nanoparticles; Limit of Detection; Luminescent Measurements; Prostatic Neoplasms; Luminescence; Antibodies, Immobilized; Reproducibility of Results
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