Optimal Selection of the Effective Echo Time (TE) for T2-Weighted Fast-Spin-Echo MRI of the Prostate at 3.0 T: Effect on Lesion Conspicuity.
2/5 보강
PICO 자동 추출 (휴리스틱, conf 2/4)
유사 논문P · Population 대상 환자/모집단
환자: suspected PCa, T values of PCa lesions and healthy tissue were measured and used to calculate the optimal TE maximizing the lesion contrast
I · Intervention 중재 / 시술
추출되지 않음
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
[EVIDENCE LEVEL] 2. [TECHNICAL EFFICACY] 2.
OpenAlex 토픽 ·
Advanced MRI Techniques and Applications
MRI in cancer diagnosis
Lanthanide and Transition Metal Complexes
[BACKGROUND] Clinical T-weighted (T2W) MRI of prostate cancer (PCa) usually implements a 2D fast-spin-echo (FSE) sequence, but understanding the echo-time-dependent contrast behavior is not straightfo
- p-value p < 0.05
APA
Dahan Kim, Ronard Pabi, et al. (2026). Optimal Selection of the Effective Echo Time (TE) for T2-Weighted Fast-Spin-Echo MRI of the Prostate at 3.0 T: Effect on Lesion Conspicuity.. Journal of magnetic resonance imaging : JMRI. https://doi.org/10.1002/jmri.70351
MLA
Dahan Kim, et al.. "Optimal Selection of the Effective Echo Time (TE) for T2-Weighted Fast-Spin-Echo MRI of the Prostate at 3.0 T: Effect on Lesion Conspicuity.." Journal of magnetic resonance imaging : JMRI, 2026.
PMID
42026845 ↗
Abstract 한글 요약
[BACKGROUND] Clinical T-weighted (T2W) MRI of prostate cancer (PCa) usually implements a 2D fast-spin-echo (FSE) sequence, but understanding the echo-time-dependent contrast behavior is not straightforward due to the complicated FSE signal evolution. Consequently, consensus-based recommendations on the optimal effective echo time (TE) to maximize contrast are lacking.
[PURPOSE] To investigate the effect of TE on PCa lesion contrast in prostate T2W MRI.
[STUDY TYPE] Phantom and in vivo prospective study.
[SUBJECTS] A standard MRI phantom and 53 prostate cancer patients (29 for image evaluation and 24 for quantitative lesion analysis).
[FIELD STRENGTH AND SEQUENCE] Multi-slice T2W FSE sequence at 3 T acquired at multiple TE values.
[ASSESSMENT] Three readers (13, 25, and 27 years' experience) evaluated TE = 100 ms versus 150 ms on diagnostic quality and reader preference. The effective T relaxation rates (T) were measured using FSE sequences in the phantom and used to predict the optimal TE maximizing T2W contrasts. From multi-TE scans of subjects with suspected PCa, T values of PCa lesions and healthy tissue were measured and used to calculate the optimal TE maximizing the lesion contrast. In vivo contrast metrics were measured as a function of TE.
[STATISTICAL TESTS] Wilcoxon test of reader scores, with p < 0.05 defining statistical significance.
[RESULTS] No statistically significant difference was found in diagnostic quality between TE = 150 ms and 100 ms images, but all three readers significantly favored TE = 150 ms. Phantom experiments demonstrated that TE-dependent FSE signal progression can be characterized by T values typically 40% longer than actual T values, allowing accurate prediction of optimal TE within 2%-5%. Applied to PCa imaging, in vivo measurements indicated that effective T relaxation times of the prostate are on average 1.5× longer than published T values.
[DATA CONCLUSION] The benefits of TE = 150 ms versus 100 ms in prostate T2W FSE were supported by reader preference, phantom experiments, in vivo measurements, and analytic optimizations.
[EVIDENCE LEVEL] 2.
[TECHNICAL EFFICACY] 2.
[PURPOSE] To investigate the effect of TE on PCa lesion contrast in prostate T2W MRI.
[STUDY TYPE] Phantom and in vivo prospective study.
[SUBJECTS] A standard MRI phantom and 53 prostate cancer patients (29 for image evaluation and 24 for quantitative lesion analysis).
[FIELD STRENGTH AND SEQUENCE] Multi-slice T2W FSE sequence at 3 T acquired at multiple TE values.
[ASSESSMENT] Three readers (13, 25, and 27 years' experience) evaluated TE = 100 ms versus 150 ms on diagnostic quality and reader preference. The effective T relaxation rates (T) were measured using FSE sequences in the phantom and used to predict the optimal TE maximizing T2W contrasts. From multi-TE scans of subjects with suspected PCa, T values of PCa lesions and healthy tissue were measured and used to calculate the optimal TE maximizing the lesion contrast. In vivo contrast metrics were measured as a function of TE.
[STATISTICAL TESTS] Wilcoxon test of reader scores, with p < 0.05 defining statistical significance.
[RESULTS] No statistically significant difference was found in diagnostic quality between TE = 150 ms and 100 ms images, but all three readers significantly favored TE = 150 ms. Phantom experiments demonstrated that TE-dependent FSE signal progression can be characterized by T values typically 40% longer than actual T values, allowing accurate prediction of optimal TE within 2%-5%. Applied to PCa imaging, in vivo measurements indicated that effective T relaxation times of the prostate are on average 1.5× longer than published T values.
[DATA CONCLUSION] The benefits of TE = 150 ms versus 100 ms in prostate T2W FSE were supported by reader preference, phantom experiments, in vivo measurements, and analytic optimizations.
[EVIDENCE LEVEL] 2.
[TECHNICAL EFFICACY] 2.
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