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Diagnostic, prognostic, and predictive biomarkers in gastric cancer: from conventional to novel biomarkers.

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Translational research : the journal of laboratory and clinical medicine 2024 Vol.274() p. 35-48
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Khalili-Tanha G, Khalili-Tanha N, Rouzbahani AK, Mahdieh R, Jasemi K, Ghaderi R

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Gastric cancer is a major health concern worldwide.

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APA Khalili-Tanha G, Khalili-Tanha N, et al. (2024). Diagnostic, prognostic, and predictive biomarkers in gastric cancer: from conventional to novel biomarkers.. Translational research : the journal of laboratory and clinical medicine, 274, 35-48. https://doi.org/10.1016/j.trsl.2024.09.001
MLA Khalili-Tanha G, et al.. "Diagnostic, prognostic, and predictive biomarkers in gastric cancer: from conventional to novel biomarkers.." Translational research : the journal of laboratory and clinical medicine, vol. 274, 2024, pp. 35-48.
PMID 39260559 ↗

Abstract

Gastric cancer is a major health concern worldwide. The survival rate of Gastric cancer greatly depends on the stage at which it is diagnosed. Early diagnosis is critical for improving survival outcomes. To improve the chances of early diagnosis, regular screening tests, such as an upper endoscopy or barium swallow, are recommended for individuals at a higher risk due to factors like family history or a previous diagnosis of gastric conditions. Biomarkers can be detected and measured using non-invasive methods such as blood tests, urine tests, breath analysis, or imaging techniques. These non-invasive approaches offer many advantages, including convenience, safety, and cost-effectiveness, making them valuable tools for disease diagnosis, monitoring, and research. Biomarker-based tests have emerged as a useful tool for identifying gastric cancer early, monitoring treatment response, assessing the recurrence risk, and personalizing treatment plans. In this current review, we have explored both classical and novel biomarkers for gastric cancer. We have centralized their potential clinical application and discussed the challenges in Gastric cancer research.

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