Prognostic Impact of Preoperative Left Ventricular Systolic Dysfunction in Older Adult Patients With Gastric Cancer.
1/5 보강
PICO 자동 추출 (휴리스틱, conf 3/4)
유사 논문P · Population 대상 환자/모집단
환자: gastric cancer has not been fully elucidated
I · Intervention 중재 / 시술
preoperative echocardiography and curative gastrectomy
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
Multivariate analysis revealed that decreased EF, low preoperative body mass index, and advanced pathological stage were significant prognostic factors in older adult patients with gastric cancer. [CONCLUSION] LVSD increases the risk of postoperative pneumonia and has a negative prognostic impact on older adult patients with gastric cancer.
[BACKGROUND/AIM] The effect of left ventricular systolic dysfunction (LVSD), a risk factor for postoperative mortality, in older adult patients with gastric cancer has not been fully elucidated.
- p-value p=0.003
- p-value p=0.016
APA
Takabatake K, Sakuramoto S, et al. (2025). Prognostic Impact of Preoperative Left Ventricular Systolic Dysfunction in Older Adult Patients With Gastric Cancer.. In vivo (Athens, Greece), 39(1), 419-425. https://doi.org/10.21873/invivo.13844
MLA
Takabatake K, et al.. "Prognostic Impact of Preoperative Left Ventricular Systolic Dysfunction in Older Adult Patients With Gastric Cancer.." In vivo (Athens, Greece), vol. 39, no. 1, 2025, pp. 419-425.
PMID
39740914 ↗
Abstract 한글 요약
[BACKGROUND/AIM] The effect of left ventricular systolic dysfunction (LVSD), a risk factor for postoperative mortality, in older adult patients with gastric cancer has not been fully elucidated. This study aimed to evaluate the impact of low preoperative left ventricular ejection fraction (EF) on short- and long-term outcomes in older adult patients with gastric cancer.
[PATIENTS AND METHODS] This retrospective study enrolled 237 older adult patients with gastric cancer (≥75 years old) who underwent preoperative echocardiography and curative gastrectomy. LVSD was defined as an EF <50%. Postoperative complications and prognosis were compared between patients with low- and normal-EF using the Fisher's exact or Chi-square test, log-rank test, Kaplan-Meier method, and Cox regression analysis.
[RESULTS] Thirteen patients (5.4%) exhibited LVSD. The incidence of postoperative complications was not significantly different between the two groups (p=0.470), although the incidence of pneumonia was high (p=0.003) and overall survival was significantly worse in the low-EF group compared to the normal-EF group (p=0.016). Multivariate analysis revealed that decreased EF, low preoperative body mass index, and advanced pathological stage were significant prognostic factors in older adult patients with gastric cancer.
[CONCLUSION] LVSD increases the risk of postoperative pneumonia and has a negative prognostic impact on older adult patients with gastric cancer.
[PATIENTS AND METHODS] This retrospective study enrolled 237 older adult patients with gastric cancer (≥75 years old) who underwent preoperative echocardiography and curative gastrectomy. LVSD was defined as an EF <50%. Postoperative complications and prognosis were compared between patients with low- and normal-EF using the Fisher's exact or Chi-square test, log-rank test, Kaplan-Meier method, and Cox regression analysis.
[RESULTS] Thirteen patients (5.4%) exhibited LVSD. The incidence of postoperative complications was not significantly different between the two groups (p=0.470), although the incidence of pneumonia was high (p=0.003) and overall survival was significantly worse in the low-EF group compared to the normal-EF group (p=0.016). Multivariate analysis revealed that decreased EF, low preoperative body mass index, and advanced pathological stage were significant prognostic factors in older adult patients with gastric cancer.
[CONCLUSION] LVSD increases the risk of postoperative pneumonia and has a negative prognostic impact on older adult patients with gastric cancer.
🏷️ 키워드 / MeSH 📖 같은 키워드 OA만
- Humans
- Stomach Neoplasms
- Male
- Female
- Aged
- Ventricular Dysfunction
- Left
- Prognosis
- 80 and over
- Postoperative Complications
- Gastrectomy
- Echocardiography
- Risk Factors
- Retrospective Studies
- Kaplan-Meier Estimate
- Stroke Volume
- Preoperative Period
- Neoplasm Staging
- Elderly patients
- complications
- gastric cancer
- left ventricular ejection fraction
- prognosis
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