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Effect of -induced gastric cancer on gastrointestinal microbiota: a narrative review.

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Frontiers in oncology 📖 저널 OA 100% 2021: 15/15 OA 2022: 98/98 OA 2023: 60/60 OA 2024: 189/189 OA 2025: 1004/1004 OA 2026: 620/620 OA 2021~2026 2024 Vol.14() p. 1495596
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Heidary M, Akrami S, Madanipour T, Shakib NH, Mahdizade Ari M, Beig M, Khoshnood S, Ghanavati R, Bazdar M

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() infection is a typical microbial agent that interferes with the complex mechanisms of gastric homeostasis by disrupting the balance between the host gastric microbiota and mucosa-related factors, u

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APA Heidary M, Akrami S, et al. (2024). Effect of -induced gastric cancer on gastrointestinal microbiota: a narrative review.. Frontiers in oncology, 14, 1495596. https://doi.org/10.3389/fonc.2024.1495596
MLA Heidary M, et al.. "Effect of -induced gastric cancer on gastrointestinal microbiota: a narrative review.." Frontiers in oncology, vol. 14, 2024, pp. 1495596.
PMID 39868371 ↗

Abstract

() infection is a typical microbial agent that interferes with the complex mechanisms of gastric homeostasis by disrupting the balance between the host gastric microbiota and mucosa-related factors, ultimately leading to inflammatory changes, dysbiosis, and gastric cancer (GC). We searched this field on the basis of PubMed, Google Scholar, Web of Science, and Scopus databases. Most studies show that inhibits the colonization of other bacteria, resulting in a less variety of bacteria in the gastrointestinal (GI) tract. When comparing the patients with positive and -negative GC, the composition of the gastric microbiome changes with increasing abundance of (where present) in the gastritis stage, whereas, as the gastric carcinogenesis cascade progresses to GC, oral and intestinal-type pathogenic microbial strains predominate. infection induces a premalignant milieu of atrophy and intestinal metaplasia, and the resulting change in gastric microbiota appears to play an important role in gastric carcinogenesis. The effect of -induced GC on GI microbiota is discussed in this review.

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