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Discordance in Claudin 18.2 Expression Between Primary and Metastatic Lesions in Patients With Gastric Cancer.

1/5 보강

Journal of gastric cancer 📖 저널 OA 100% 2025~2026 2025 Vol.25(2) p. 303-317

PICO 자동 추출 (휴리스틱, conf 2/4)

P · Population 대상 환자/모집단

[MATERIALS AND METHODS] We retrospectively analyzed data from 102 patients with pathologically confirmed paired primary and metastatic gastric or gastroesophageal junction adenocarcinomas.

I · Intervention 중재 / 시술

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C · Comparison 대조 / 비교

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O · Outcome 결과 / 결론

[CONCLUSIONS] CLDN18.2 expression demonstrates significant heterogeneity between PGC and MGC, with a 20% discordance rate. Comprehensive tissue sampling and reassessment of CLDN18.2 status are crucial, especially before initiating CLDN18.2-targeted therapies.

Son SM, Woo CG, Lee OJ, Lee SK, Cho M, Lee YP

📖 무료 전문 🟢 PMC 전문 PMC11982508

PubMed ↗ DOI ↗ BibTeX ↓ RIS ↓

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