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How is single-cell RNA sequencing contributing to the advancement of cancer therapeutics?

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World journal of gastrointestinal oncology 📖 저널 OA 100% 2024: 14/14 OA 2025: 188/188 OA 2026: 44/44 OA 2024~2026 2025 Vol.17(4) p. 103480
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Jeong KY

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The study of Tang investigated the distribution and dynamic changes of cell populations in the tumor microenvironment of gastric cancer (GC) patients using single-cell RNA sequencing (scRNA-seq).

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APA Jeong KY (2025). How is single-cell RNA sequencing contributing to the advancement of cancer therapeutics?. World journal of gastrointestinal oncology, 17(4), 103480. https://doi.org/10.4251/wjgo.v17.i4.103480
MLA Jeong KY. "How is single-cell RNA sequencing contributing to the advancement of cancer therapeutics?." World journal of gastrointestinal oncology, vol. 17, no. 4, 2025, pp. 103480.
PMID 40235873 ↗

Abstract

The study of Tang investigated the distribution and dynamic changes of cell populations in the tumor microenvironment of gastric cancer (GC) patients using single-cell RNA sequencing (scRNA-seq). This comprehensive analysis highlights key interactions within the tumor microenvironment across different GC stages. Discussing applications of scRNA-seq data in clinical settings could pave the way for developing promising and personalized therapeutic strategies for GC patients. Therefore, further exploration of selecting anticancer drug candidates through gene screening derived from scRNA-seq will provide deeper insights into GC care.

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