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Lymphangiosis Carcinomatosa of the Liver and Extrahepatic Bile Duct Due to Gastric Cancer: A Case Report and Literature Review.

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Internal medicine (Tokyo, Japan) 📖 저널 OA 77.9% 2024: 6/6 OA 2025: 37/56 OA 2026: 71/84 OA 2024~2026 2025 Vol.64(9) p. 1321-1326
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Koya Y, Hanada S, Murakami T, Miyagawa K, Maruno Y, Yamaguchi K

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A 78-year-old man was diagnosed with advanced poorly differentiated gastric adenocarcinoma, presenting with jaundice and diffuse thickening of the extrahepatic bile duct.

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APA Koya Y, Hanada S, et al. (2025). Lymphangiosis Carcinomatosa of the Liver and Extrahepatic Bile Duct Due to Gastric Cancer: A Case Report and Literature Review.. Internal medicine (Tokyo, Japan), 64(9), 1321-1326. https://doi.org/10.2169/internalmedicine.4357-24
MLA Koya Y, et al.. "Lymphangiosis Carcinomatosa of the Liver and Extrahepatic Bile Duct Due to Gastric Cancer: A Case Report and Literature Review.." Internal medicine (Tokyo, Japan), vol. 64, no. 9, 2025, pp. 1321-1326.
PMID 39293974 ↗

Abstract

A 78-year-old man was diagnosed with advanced poorly differentiated gastric adenocarcinoma, presenting with jaundice and diffuse thickening of the extrahepatic bile duct. No obstructive biliary sites or liver masses were observed. The serum concentrations of proteins induced by the absence of vitamin K or antagonist-II were markedly high. Samples of the extrahepatic bile duct and liver were obtained by endoscopic examination. The patient was diagnosed with lymphangiosis carcinomatosa of the liver and extrahepatic bile duct but died 28 days after hospitalization. As the disease progresses rapidly with uncharacteristic imaging findings, biopsy samples should be obtained early using several diagnostic tools.

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