Impact of cancer-directed surgery for gastric cancer patients with lung metastasis: a prognosis analysis.
1/5 보강
PICO 자동 추출 (휴리스틱, conf 2/4)
유사 논문P · Population 대상 환자/모집단
환자: lung metastatic gastric cancer (LMGC) was investigated in this study
I · Intervention 중재 / 시술
추출되지 않음
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
Furthermore, the multivariate Cox regression analysis after PSM indicated that chemotherapy [hazard ratio (HR) = 0.35, 95% confidence interval (CI): 0.30-0.40, P<0.001] and CDS (HR =0.50, 95% CI: 0.38-0.67, P<0.001) were associated to favorable OS for LMGC patients. [CONCLUSIONS] CDS may improve the prognosis of patients with LMGC.
[BACKGROUND] Gastric cancer (GC) is acknowledged as a fatal malignant disease.
- p-value P=0.03
- p-value P<0.001
- 95% CI 0.38-0.67
- HR 0.50
APA
Tan Z, Du X, et al. (2025). Impact of cancer-directed surgery for gastric cancer patients with lung metastasis: a prognosis analysis.. Journal of gastrointestinal oncology, 16(3), 890-898. https://doi.org/10.21037/jgo-2024-976
MLA
Tan Z, et al.. "Impact of cancer-directed surgery for gastric cancer patients with lung metastasis: a prognosis analysis.." Journal of gastrointestinal oncology, vol. 16, no. 3, 2025, pp. 890-898.
PMID
40672099 ↗
Abstract 한글 요약
[BACKGROUND] Gastric cancer (GC) is acknowledged as a fatal malignant disease. The impact of cancer-directed surgery (CDS) on the prognosis of patients with lung metastatic gastric cancer (LMGC) was investigated in this study.
[METHODS] The clinical data of LMGC patients after CDS were obtained from the Surveillance, Epidemiology, and End Results (SEER) database [2000-2020]. This study used the R software to perform propensity score matching (PSM). Then, the influence of different variables on overall survival (OS) was measured by Cox regression analysis and Kaplan-Meier curve analysis.
[RESULTS] A total of 1,045 LMGC patients were included in the present study. Among these patients, 970 (92.82%) patients were assigned to the non-CDS group and 75 (7.18%) were assigned to the CDS group. After PSM, 165 (72.37%) patients in the non-CDS group and 63 (27.63%) patients in the CDS group were identified. The Kaplan-Meier analysis results revealed that the median OS was significantly longer in the CDS group (12 6 months, P=0.03). Furthermore, the multivariate Cox regression analysis after PSM indicated that chemotherapy [hazard ratio (HR) = 0.35, 95% confidence interval (CI): 0.30-0.40, P<0.001] and CDS (HR =0.50, 95% CI: 0.38-0.67, P<0.001) were associated to favorable OS for LMGC patients.
[CONCLUSIONS] CDS may improve the prognosis of patients with LMGC.
[METHODS] The clinical data of LMGC patients after CDS were obtained from the Surveillance, Epidemiology, and End Results (SEER) database [2000-2020]. This study used the R software to perform propensity score matching (PSM). Then, the influence of different variables on overall survival (OS) was measured by Cox regression analysis and Kaplan-Meier curve analysis.
[RESULTS] A total of 1,045 LMGC patients were included in the present study. Among these patients, 970 (92.82%) patients were assigned to the non-CDS group and 75 (7.18%) were assigned to the CDS group. After PSM, 165 (72.37%) patients in the non-CDS group and 63 (27.63%) patients in the CDS group were identified. The Kaplan-Meier analysis results revealed that the median OS was significantly longer in the CDS group (12 6 months, P=0.03). Furthermore, the multivariate Cox regression analysis after PSM indicated that chemotherapy [hazard ratio (HR) = 0.35, 95% confidence interval (CI): 0.30-0.40, P<0.001] and CDS (HR =0.50, 95% CI: 0.38-0.67, P<0.001) were associated to favorable OS for LMGC patients.
[CONCLUSIONS] CDS may improve the prognosis of patients with LMGC.
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