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Potential Value of AURKA and CDK6 Amplification for the Response of Patients With Gastric Cancer to Neoadjuvant Chemotherapy.

1/5 보강
Molecular carcinogenesis 📖 저널 OA 24.7% 2023: 0/1 OA 2024: 0/9 OA 2025: 3/27 OA 2026: 14/43 OA 2023~2026 2025 Vol.64(7) p. 1195-1208
Retraction 확인
출처
PubMed DOI

PICO 자동 추출 (휴리스틱, conf 2/4)

유사 논문
P · Population 대상 환자/모집단
18 patients with advanced stomach cancer who were treated with NACT categorized according to tumor regression grade into major histological response (MJHR) and nonhistological response (NHR) groups were retrospectively analyzed.
I · Intervention 중재 / 시술
추출되지 않음
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
These findings support the potential value of AURKA and CDK6 amplification, as well as their effects on the tumor microenvironment, in predicting poor outcomes of NACT in patients with locally advanced gastric cancer. Thus, CDK4/6 inhibitors could be used to treat NACT-resistant patients with gastric cancer.

Tan Y, Xing Y, Yuan S, Sun F, Lin X, Bao S

PubMed ↗ DOI ↗ BibTeX ↓ RIS ↓

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