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Autoimmune Gastritis and Infection: Molecular Mechanisms of Relationship.

International journal of molecular sciences 2025 Vol.26(16)

Bordin DS, Livzan MA, Mozgovoi SI, Gaus OV

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() infection and autoimmune inflammation of the gastric mucosa are recognized as the leading etiological factors of chronic atrophic gastritis.

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APA Bordin DS, Livzan MA, et al. (2025). Autoimmune Gastritis and Infection: Molecular Mechanisms of Relationship.. International journal of molecular sciences, 26(16). https://doi.org/10.3390/ijms26167737
MLA Bordin DS, et al.. "Autoimmune Gastritis and Infection: Molecular Mechanisms of Relationship.." International journal of molecular sciences, vol. 26, no. 16, 2025.
PMID 40869058

Abstract

() infection and autoimmune inflammation of the gastric mucosa are recognized as the leading etiological factors of chronic atrophic gastritis. The mechanisms of atrophy formation and progression with the risk of gastric cancer development are heterogeneous, which requires a deeper study of the molecular mechanisms of relationship, peculiarities of the course of autoimmune gastritis both in combination with and after eradication, as well as without infection (naïve AIG). This article presents the specific molecular and cellular patterns in the formation of these related conditions.

MeSH Terms

Helicobacter Infections; Humans; Helicobacter pylori; Autoimmune Diseases; Gastritis; Gastric Mucosa; Gastritis, Atrophic; Stomach Neoplasms; Animals