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A Case of Neurofibromatosis Type 1 With Early Gastric Cancer and Multiple Small Bowel Gastrointestinal Stromal Tumors.

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The Korean journal of helicobacter and upper gastrointestinal research 📖 저널 OA 100% 2024: 4/4 OA 2025: 17/17 OA 2026: 8/8 OA 2024~2026 2025 Vol.25(3) p. 292-295
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Ahn D, Cho YK, Choi IH, Kim S, Kim I, Kang D

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Neurofibromatosis type 1 (NF1) is a multisystem genetic disorder that primarily affects the skin and nervous system, leading to characteristic skin changes and the development of benign or malignant t

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APA Ahn D, Cho YK, et al. (2025). A Case of Neurofibromatosis Type 1 With Early Gastric Cancer and Multiple Small Bowel Gastrointestinal Stromal Tumors.. The Korean journal of helicobacter and upper gastrointestinal research, 25(3), 292-295. https://doi.org/10.7704/kjhugr.2025.0034
MLA Ahn D, et al.. "A Case of Neurofibromatosis Type 1 With Early Gastric Cancer and Multiple Small Bowel Gastrointestinal Stromal Tumors.." The Korean journal of helicobacter and upper gastrointestinal research, vol. 25, no. 3, 2025, pp. 292-295.
PMID 40935631 ↗

Abstract

Neurofibromatosis type 1 (NF1) is a multisystem genetic disorder that primarily affects the skin and nervous system, leading to characteristic skin changes and the development of benign or malignant tumors with a broad spectrum of severity and complications. Gastrointestinal stromal tumors (GISTs) are the most common non-neurological tumors occurring in patients with NF1. The clinical, genetic, and pathological features of these tumors differ significantly from those of sporadic GISTs. Very rarely, other gastrointestinal malignancies, such as small bowel adenocarcinomas, neuroendocrine tumors, and gastric adenocarcinomas, have occurred in patients with NF1. Here, we report a case of multiple duodenal GISTs and early gastric cancer in a patient with NF1.

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