Linitis Plastica in a Patient With a BRCA2 Mutation: A Case Report.
증례보고
1/5 보강
pathogenic mutations are well-established risk factors for breast, ovarian, prostate, and pancreatic cancers.
APA
Park S, Cao E, Amar S (2026). Linitis Plastica in a Patient With a BRCA2 Mutation: A Case Report.. Cureus, 18(1), e102423. https://doi.org/10.7759/cureus.102423
MLA
Park S, et al.. "Linitis Plastica in a Patient With a BRCA2 Mutation: A Case Report.." Cureus, vol. 18, no. 1, 2026, pp. e102423.
PMID
41769559
Abstract
pathogenic mutations are well-established risk factors for breast, ovarian, prostate, and pancreatic cancers. However, the relationship between mutations and gastric cancer (GC) remains understudied. This case involves a patient with a pathogenic mutation diagnosed with linitis plastica, a diffuse form of GC characterized by stiffening of the gastric lining, akin to a "leather bottle." This case highlights the importance of further research to elucidate the connection between GC and mutations, which may lead to expanded surveillance guidelines for affected individuals. Clinicians should consider the potential elevated risk of GC in patients with mutations.
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