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Recent advances in spasmolytic polypeptide expressing metaplasia research.

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World journal of gastrointestinal oncology 📖 저널 OA 100% 2024: 14/14 OA 2025: 188/188 OA 2026: 44/44 OA 2024~2026 2026 Vol.18(2) p. 113995
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Yang RR, Yan YR, Li YF

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Gastric cancer remains a leading cause of global cancer mortality, with limited advances in its prevention and treatment owing to an incomplete understanding of its pathogenesis.

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APA Yang RR, Yan YR, Li YF (2026). Recent advances in spasmolytic polypeptide expressing metaplasia research.. World journal of gastrointestinal oncology, 18(2), 113995. https://doi.org/10.4251/wjgo.v18.i2.113995
MLA Yang RR, et al.. "Recent advances in spasmolytic polypeptide expressing metaplasia research.." World journal of gastrointestinal oncology, vol. 18, no. 2, 2026, pp. 113995.
PMID 41695940 ↗

Abstract

Gastric cancer remains a leading cause of global cancer mortality, with limited advances in its prevention and treatment owing to an incomplete understanding of its pathogenesis. Among the key precancerous lesions, spasmolytic polypeptide-expressing metaplasia has emerged as a critical driver in gastric carcinogenesis. This review summarizes the recent advances in the mechanistic roles of spasmolytic polypeptide-expressing metaplasia in gastric mucosal diseases. By elucidating these pathways, this review sought to provide novel insights that could inform future strategies for early intervention and prevention of gastric cancer.

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