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Cerebral infarctions caused by pulmonary vein metastasis from gastric cancer: A case report.

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Oncology letters 2026 Vol.31(3) p. 116
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Hara N, Yoshii Y, Kojitani Y, Sasaki R, Ota M, Okazaki S, Nakagawa H, Takemura J, Miyata R, Hamaji M, Hosono M, Okada F, Yoshizawa A, Takeda M

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Gastric cancer remains one of the leading causes of cancer-related mortality worldwide, particularly in East Asian countries, despite advances in systemic therapy and the development of novel targeted

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APA Hara N, Yoshii Y, et al. (2026). Cerebral infarctions caused by pulmonary vein metastasis from gastric cancer: A case report.. Oncology letters, 31(3), 116. https://doi.org/10.3892/ol.2026.15469
MLA Hara N, et al.. "Cerebral infarctions caused by pulmonary vein metastasis from gastric cancer: A case report.." Oncology letters, vol. 31, no. 3, 2026, pp. 116.
PMID 41640458

Abstract

Gastric cancer remains one of the leading causes of cancer-related mortality worldwide, particularly in East Asian countries, despite advances in systemic therapy and the development of novel targeted and immune-based treatments. Due to its aggressive biological behavior, gastric cancer frequently metastasizes to the liver, peritoneum, lymph nodes, lungs and bone. Although extremely rare, pulmonary vein metastasis is clinically significant as it can cause embolic events in vital organs, including multiple cerebral infarctions. The present report describes an extremely rare case of cerebral infarction secondary to pulmonary vein metastasis originating from a gastric adenocarcinoma. To the best of our knowledge, the current case is the first documented case of its kind.