Helicobacter pylori Positivity by 16S rRNA Gene PCR in Fecal Samples From Patients With Gastroduodenal Symptoms: A Retrospective Observational Study.
1/5 보강
PICO 자동 추출 (휴리스틱, conf 2/4)
유사 논문P · Population 대상 환자/모집단
환자: gastroduodenal symptoms were analyzed
I · Intervention 중재 / 시술
추출되지 않음
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
[CONCLUSIONS] The positivity rate for H. pylori (70%) was confirmed by PCR, indicating that molecular testing of fecal samples is an effective non-invasive tool for detecting infection.
[OBJECTIVES] Helicobacter pylori is recognized as one of the most virulent microorganisms within the genus Helicobacter owing to its genomic characteristics.
APA
Jácome-Montero D, Guamán-Angulo J, et al. (2026). Helicobacter pylori Positivity by 16S rRNA Gene PCR in Fecal Samples From Patients With Gastroduodenal Symptoms: A Retrospective Observational Study.. The Korean journal of helicobacter and upper gastrointestinal research, 26(1), 68-72. https://doi.org/10.7704/kjhugr.2025.0067
MLA
Jácome-Montero D, et al.. "Helicobacter pylori Positivity by 16S rRNA Gene PCR in Fecal Samples From Patients With Gastroduodenal Symptoms: A Retrospective Observational Study.." The Korean journal of helicobacter and upper gastrointestinal research, vol. 26, no. 1, 2026, pp. 68-72.
PMID
41846447 ↗
Abstract 한글 요약
[OBJECTIVES] Helicobacter pylori is recognized as one of the most virulent microorganisms within the genus Helicobacter owing to its genomic characteristics. It has been associated with diseases, such as peptic ulcers and gastric cancer. This study aimed to evaluate Helicobacter pylori positivity in fecal samples using 16S rRNA gene polymerase chain reaction (PCR) in fecal samples.
[METHODS] Fecal samples from patients with gastroduodenal symptoms were analyzed. Stool antigen test (SAT) was performed to identify H. pylori-positive cases. Subsequently, a pre-enrichment step was performed to increase the bacterial DNA yield and improve the molecular detection efficiency. Finally, PCR amplification, targeting a specific region of the H. pylori 16S rRNA gene, was performed to confirm the presence of the pathogen.
[RESULTS] A 70% PCR positivity rate was observed among SAT-positive samples amplified for the 16S rRNA gene.
[CONCLUSIONS] The positivity rate for H. pylori (70%) was confirmed by PCR, indicating that molecular testing of fecal samples is an effective non-invasive tool for detecting infection.
[METHODS] Fecal samples from patients with gastroduodenal symptoms were analyzed. Stool antigen test (SAT) was performed to identify H. pylori-positive cases. Subsequently, a pre-enrichment step was performed to increase the bacterial DNA yield and improve the molecular detection efficiency. Finally, PCR amplification, targeting a specific region of the H. pylori 16S rRNA gene, was performed to confirm the presence of the pathogen.
[RESULTS] A 70% PCR positivity rate was observed among SAT-positive samples amplified for the 16S rRNA gene.
[CONCLUSIONS] The positivity rate for H. pylori (70%) was confirmed by PCR, indicating that molecular testing of fecal samples is an effective non-invasive tool for detecting infection.
🏷️ 키워드 / MeSH 📖 같은 키워드 OA만
🏷️ 같은 키워드 · 무료전문 — 이 논문 MeSH/keyword 기반
- Journey Towards Piloting Helicobacter pylori Screen-and-Treat to Address Health Inequities in Aotearoa New Zealand.
- Gastric intestinal metaplasia: Management and surveillance strategies.
- Practice Tips From the Updated Treatment Guidelines.
- -related non-coding RNAs in gastric cancer screening: Emerging evidence and translational challenges.
- Vitamin D receptor gene polymorphism and its association with the susceptibility to Helicobacter pylori infection in the Egyptian population with hepatocellular carcinoma.
- Hepatitis B Virus, and High-Risk Events of Gastric Cancer Development: An Observational Study (SIGES).