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A review of the relationship between type 2 diabetes mellitus and different stages of hepatitis B infection (HCC, CHB, OBI).

Microbial pathogenesis 2025 Vol.206() p. 107748

Kareem RA, Sameer HN, Athab ZH, Adil M, Yaseen A, Allela OQB

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A chronic condition known as diabetes develops when the pancreas does not generate insulin or the body cannot utilize the insulin it produces correctly.

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BibTeX ↓ RIS ↓
APA Kareem RA, Sameer HN, et al. (2025). A review of the relationship between type 2 diabetes mellitus and different stages of hepatitis B infection (HCC, CHB, OBI).. Microbial pathogenesis, 206, 107748. https://doi.org/10.1016/j.micpath.2025.107748
MLA Kareem RA, et al.. "A review of the relationship between type 2 diabetes mellitus and different stages of hepatitis B infection (HCC, CHB, OBI).." Microbial pathogenesis, vol. 206, 2025, pp. 107748.
PMID 40419198

Abstract

A chronic condition known as diabetes develops when the pancreas does not generate insulin or the body cannot utilize the insulin it produces correctly. Viruses may drive metabolic disorders. Some research suggests that viral infections may play a role in developing type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM). If we want to know how viruses directly affect diabetes mellitus (DM), we need more long-term observational studies that began after viral outbreaks. For instance, more than one study has linked the hepatitis C virus (HCV) to an increased risk of T2DM. Furthermore, T2DM and hepatitis B virus (HBV) infection are major global health concerns. There may be a connection between the two illnesses, but researchers are unsure exactly what it is. Clinicians can develop more effective methods for preventing and treating T2DM and HBV infection if the possible roles of the two conditions are better understood. This article thoroughly examines T2DM and its correlation with the phases of hepatitis B infection (hepatocellular carcinoma, chronic HBV, occult hepatitis B infection). We also looked at the associations between T2DM and several viruses, including those that cause the disease and those associated with it, such as HBV, HCV, and HPV.

MeSH Terms

Diabetes Mellitus, Type 2; Humans; Hepatitis B; Carcinoma, Hepatocellular; Liver Neoplasms; Hepatitis B, Chronic; Hepatitis B virus