Hepatitis viruses hijack cellular metabolic pathways to drive replication and disease: Implications for novel therapeutics.
Hepatitis viruses are one of the most common viruses threatening humans all over the world, which can lead to viral hepatitis and even increase the risk of hepatocellular carcinoma.
APA
Peng N, Lin Q, et al. (2025). Hepatitis viruses hijack cellular metabolic pathways to drive replication and disease: Implications for novel therapeutics.. Microbial pathogenesis, 206, 107837. https://doi.org/10.1016/j.micpath.2025.107837
MLA
Peng N, et al.. "Hepatitis viruses hijack cellular metabolic pathways to drive replication and disease: Implications for novel therapeutics.." Microbial pathogenesis, vol. 206, 2025, pp. 107837.
PMID
40578709
Abstract
Hepatitis viruses are one of the most common viruses threatening humans all over the world, which can lead to viral hepatitis and even increase the risk of hepatocellular carcinoma. Numerous investigations have shown that hepatitis viruses reprogram the metabolisms of infected cells, including alterations in glucose, amino acid, and lipid metabolic pathways, resulting in changes of the life cycles of viruses, the status of host cells and the development of diseases. In this review, we summarized how hepatitis viruses rewire cells' metabolisms to promote virus replication and pathogenesis, which contributes to the exploitation of potential therapeutic paradigms.
MeSH Terms
Humans; Virus Replication; Metabolic Networks and Pathways; Hepatitis Viruses; Hepatitis, Viral, Human; Host-Pathogen Interactions; Lipid Metabolism; Antiviral Agents; Animals; Glucose
같은 제1저자의 인용 많은 논문 (5)
- Foundations of Artificial Intelligence in Hepatology: What a Clinician Needs to Know.
- HES V2.0: Advancing biomarker-based surveillance for HCC - promise and remaining gaps.
- Correction: The efficacy and safety of tislelizumab with or without tyrosine kinase inhibitor as adjuvant therapy in hepatocellular carcinoma with high-risk of recurrence after curative resection.
- "Sample-in, result-out" liquid biopsy chip based on immunomagnetic separation and CRISPR detection for multiplex analysis of exosomal microRNAs.
- PARP inhibitors for HRR-deficient metastatic castration-resistant prostate cancer: mechanisms and clinical strategies.