Carbofilm-covered prostheses in plastic surgery: preliminary observations.

Plastic and reconstructive surgery 1993 Vol.91(1) p. 80-8; discussion 89-90

Bocchiotti G, Verna G, Fracalvieri M, Fanton E, Datta G, Robotti E

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Abstract

The optimal interface between an implant and the host organism is that which minimizes uncontrolled and irregular growth of fibrous tissue around the foreign material. One way to achieve this goal is to coat the outer surface of the implant with a biocompatible material. A thin film of turbostratic carbon (Carbofilm, Sorin Biomedica, Saluggia, Italy) can be applied as a thin coating on tissue expanders and breast implants made of silicone elastomers. The success of biologic trials with such implants in rats and cytologic studies with murine and human fibroblasts encouraged us to employ the Carbofilm technology in clinical situations. Preliminary results indicate that Carbofilm-coated implants satisfy the requirements of an ideal alloplastic material and induce a minimal periprosthetic inflammatory reaction, with the formation of a thin, soft, pliable, fibrous capsule around coated gel-filled silicone implants.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
해부 tissue scispacy 1
해부 periprosthetic inflammatory scispacy 1
해부 breast 유방 dict 1
합병증 alloplastic material scispacy 1
약물 carbon → Carbofilm, Sorin Biomedica, Saluggia, Italy scispacy 1
약물 silicone C0037114
silicones
scispacy 1
질환 fibrous C0439709
Fibrous
scispacy 1
질환 cytologic scispacy 1
질환 capsule scispacy 1
기타 tissue expanders scispacy 1
기타 rats scispacy 1
기타 murine scispacy 1
기타 human fibroblasts scispacy 1

MeSH Terms

Animals; Biocompatible Materials; Cells, Cultured; Contracture; Female; Fibroblasts; Foreign-Body Reaction; Humans; Mammaplasty; Polyurethanes; Prostheses and Implants; Rats; Silicone Elastomers; Silicones; Surface Properties; Surgery, Plastic; Tissue Expansion Devices

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