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Small intestinal metastasis of hepatocellular carcinoma diagnosed and resected as intestinal obstruction caused by a foreign body.

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Journal of surgical case reports 2025 Vol.2025(9) p. rjaf679
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Matsuda M, Yoshiya S, Kawada I, Nakamura S, Tada K, Ito K, Koso H, Kuroda Y, Yoshizumi F, Iwaki K, Hiroshige S, Yamashita YI, Takeuchi H, Yoshizumi T, Fukuzawa K

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Hematogenous metastases of hepatocellular carcinoma (HCC) to the small intestine are rare.

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APA Matsuda M, Yoshiya S, et al. (2025). Small intestinal metastasis of hepatocellular carcinoma diagnosed and resected as intestinal obstruction caused by a foreign body.. Journal of surgical case reports, 2025(9), rjaf679. https://doi.org/10.1093/jscr/rjaf679
MLA Matsuda M, et al.. "Small intestinal metastasis of hepatocellular carcinoma diagnosed and resected as intestinal obstruction caused by a foreign body.." Journal of surgical case reports, vol. 2025, no. 9, 2025, pp. rjaf679.
PMID 40909379

Abstract

Hematogenous metastases of hepatocellular carcinoma (HCC) to the small intestine are rare. In most cases, hematogenous metastasis is symptomatic, including perforation or bleeding, and the prognosis is poor. A 63-year-old man had lower right abdominal pain, and small intestinal obstruction due to chronic inflammation of the foreign body was suspected on computed tomography. Blood tests revealed elevated alpha-fetoprotein (AFP). He had undergone four surgeries for HCC. Conservative treatment was administered, but there was little improvement. A segmental resection of the small intestine was performed. A type 2 tumor was found in the resected specimen, and pathological examination led to a diagnosis of HCC metastasis in the small intestine. He survived without recurrence for 10 months after surgery. When a patient with a history of HCC treatment develops intestinal obstruction or intussusception, it is necessary to consider the possibility of small intestinal metastasis, especially if there is an increase in AFP.

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