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Zuojin capsule improves T cell exhaustion and tumor immune microenvironment of hepatocellular carcinoma through the mTOR-eIF4E/p70S6K-CDK1 pathway.

1/5 보강

Frontiers in immunology 📖 저널 OA 100% 2021~2026 2025 Vol.16() p. 1617604

PICO 자동 추출 (휴리스틱, conf 2/4)

유사 논문

P · Population 대상 환자/모집단

추출되지 않음

I · Intervention 중재 / 시술

ZJC or anti-PD-1 to evaluate tumor growth and immune responses

C · Comparison 대조 / 비교

추출되지 않음

O · Outcome 결과 / 결론

In addition, the control group showed relatively high positive staining for CD163, whereas ZJC and anti-PD-1 inhibited the expression or aggregation of CD163-positive cells. [CONCLUSION] ZJC exerts dual anti-tumor effects by inhibiting the mTOR-eIF4E/p70S6K-CDK1 pathway and remodeling the immunosuppressive microenvironment of HCC.

Hao L, Li S, Deng J, Hu X

📖 무료 전문 🟢 PMC 전문 PMC12497796

PubMed ↗ DOI ↗ BibTeX ↓ RIS ↓

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