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PNPLA3 polymorphism worsens chemotherapy associated liver injury and affects overall survival in colorectal cancer patients with liver metastasis undergoing hepatic resection.

1/5 보강

EBioMedicine 📖 저널 OA 98.2% 2022~2026 2025 Vol.120() p. 105928

PICO 자동 추출 (휴리스틱, conf 3/4)

유사 논문

P · Population 대상 환자/모집단

551 patients with CRLM undergoing liver surgery after NAC were included.

I · Intervention 중재 / 시술

funding related to the writing of this manuscript

C · Comparison 대조 / 비교

추출되지 않음

O · Outcome 결과 / 결론

Considering that PNPLA3 polymorphisms are significantly higher in Asian populations, these results could partly explain the heterogeneity in reported effects of NAC in CRLM patients and might improve patient selection. [FUNDING] None of the authors received funding related to the writing of this manuscript.

Rumpf B, Santol J, Kern AE, Ammann M, Probst J, Baumgartner R

📖 무료 전문 🟢 PMC 전문 PMC12466148

PubMed ↗ DOI ↗ BibTeX ↓ RIS ↓

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