Engineered nanomedicine targets liver cancer stem cells to treat liver cancer disease.
1/5 보강
Liver cancer stem cells (LCSCs) are a population of cells with self-renewal and self-differentiation capacities, widely recognized as critical for hepatocellular carcinoma (HCC) development.
APA
Huang F, Chen L, et al. (2025). Engineered nanomedicine targets liver cancer stem cells to treat liver cancer disease.. Journal of materials chemistry. B, 13(41), 13184-13205. https://doi.org/10.1039/d5tb01278c
MLA
Huang F, et al.. "Engineered nanomedicine targets liver cancer stem cells to treat liver cancer disease.." Journal of materials chemistry. B, vol. 13, no. 41, 2025, pp. 13184-13205.
PMID
41002238 ↗
Abstract 한글 요약
Liver cancer stem cells (LCSCs) are a population of cells with self-renewal and self-differentiation capacities, widely recognized as critical for hepatocellular carcinoma (HCC) development. Accordingly, eliminating LCSCs is considered a viable strategy for HCC treatment. However, conventional chemotherapy and radiation therapy struggle to eradicate LCSCs, underscoring the critical need for LCSC-targeted therapies. Nanotechnology offers unique advantages for LCSC targeting the selective delivery of drugs to tumor sites. Various engineered nanomedicines-including polymeric nanoparticles, biological nanomaterials, and inorganic nanoparticles-have been developed for their elimination. This article primarily reviews the biological concepts and biomarkers of LCSCs. In addition, it summarizes various strategies for targeting LCSCs using engineered nanomedicines.
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