An unusual late reaction to Zyderm I injections: a challenge for treatment.
Abstract
We describe a patient who, 2 1/2 years after injection with Zyderm I collagen, developed large erythematous indurated nodules and plaques at the facial injection sites. This occurred despite a prior negative skin test with the injectable material. Histopathologically, a sarcoid-like foreign-body reaction was present in the dermis and subcutaneous fat and muscles. Retesting with Zyderm I collagen on the forearm produced a positive reaction that showed, histologically, a sarcoid-like reaction similar to that which was found in the face. Various modes of therapy have failed to clear the facial lesions and disfigurement.
추출된 의학 개체 (NER)
| 유형 | 영어 표현 | 한국어 / 풀이 | UMLS CUI | 출처 | 등장 |
|---|---|---|---|---|---|
| 해부 | subcutaneous fat
|
scispacy | 1 | ||
| 해부 | muscles
|
scispacy | 1 | ||
| 해부 | forearm
|
scispacy | 1 | ||
| 해부 | subcutaneous
|
피하조직 | dict | 1 | |
| 해부 | skin
|
scispacy | 1 | ||
| 해부 | dermis
|
scispacy | 1 | ||
| 합병증 | facial lesions
|
scispacy | 1 | ||
| 합병증 | erythematous indurated
|
scispacy | 1 | ||
| 질환 | sarcoid-like
|
scispacy | 1 | ||
| 질환 | sarcoid-like foreign-body reaction
|
scispacy | 1 | ||
| 기타 | Zyderm I
|
scispacy | 1 | ||
| 기타 | patient
|
scispacy | 1 | ||
| 기타 | collagen
|
scispacy | 1 | ||
| 기타 | sarcoid-like foreign-body
|
scispacy | 1 |
MeSH Terms
Adult; Biopsy; Collagen; Female; Foreign-Body Reaction; Humans; Hypersensitivity, Delayed; Lip Diseases; Skin Tests; Surgery, Plastic; Time Factors
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