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Intracardiac Mass Reveals Hepatocellular Carcinoma: A Rare Case of Cardiac Metastasis.

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Cureus 📖 저널 OA 99.9% 2021: 42/43 OA 2022: 79/79 OA 2023: 181/181 OA 2024: 284/284 OA 2025: 774/774 OA 2026: 506/506 OA 2021~2026 2025 Vol.17(11) p. e97501
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Abdelrahman T, Ali M, Ahmed A, Rangarajan H

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A well-known cause of emergency admission in the elderly is falls, which can be the initial manifestation of severe underlying diseases.

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APA Abdelrahman T, Ali M, et al. (2025). Intracardiac Mass Reveals Hepatocellular Carcinoma: A Rare Case of Cardiac Metastasis.. Cureus, 17(11), e97501. https://doi.org/10.7759/cureus.97501
MLA Abdelrahman T, et al.. "Intracardiac Mass Reveals Hepatocellular Carcinoma: A Rare Case of Cardiac Metastasis.." Cureus, vol. 17, no. 11, 2025, pp. e97501.
PMID 41439075 ↗

Abstract

A well-known cause of emergency admission in the elderly is falls, which can be the initial manifestation of severe underlying diseases. This case illustrates an incidental diagnosis of advanced hepatocellular carcinoma (HCC) with vascular invasion after a fall in a middle-aged man. The patient presented with a mechanical fall at night, with a medical background of severe chronic obstructive pulmonary disease (COPD), type 2 diabetes mellitus, ischemic heart disease, and obesity, at 79 years of age. There was no history of previous chest pain, dizziness, or any neurological problems. On physical assessment, there was bilateral knee swelling with bruising, and a swollen right ankle. Initial studies showed elevated cardiac biomarkers and ECG changes, raising concern for a silent myocardial infarction. A 2D echocardiogram revealed a proliferative right atrial mass and a hepatic lesion, raising suspicion for a tumor. A contrast-enhanced CT scan subsequently confirmed liver cirrhosis and a large hepatic mass extending into the portal vein, inferior vena cava (IVC), and right atrium (RA), consistent with advanced HCC. The patient's comorbidities and poor performance status prompted the multidisciplinary team to recommend best supportive care only. This case highlights the importance of a thorough evaluation of elderly patients presenting with falls. It demonstrates how a routine admission can lead to the incidental diagnosis of an advanced malignancy. The case also underscores the need for close attention to unusual symptoms in chronically ill patients, particularly when they may harbor a silent, undiagnosed disease or cancer such as HCC.

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