A case of colon cancer with secondary pancreatic head metastasis treated via radioactive iodine-125 seed implantation.
[INTRODUCTION] Metastatic pancreatic tumors are rare, accounting for only 2 % of pancreatic malignancies, with colon cancer representing just 1.3 % of these cases.
APA
Ma CW, Zheng J, et al. (2025). A case of colon cancer with secondary pancreatic head metastasis treated via radioactive iodine-125 seed implantation.. International journal of surgery case reports, 136, 111968. https://doi.org/10.1016/j.ijscr.2025.111968
MLA
Ma CW, et al.. "A case of colon cancer with secondary pancreatic head metastasis treated via radioactive iodine-125 seed implantation.." International journal of surgery case reports, vol. 136, 2025, pp. 111968.
PMID
40987219
Abstract
[INTRODUCTION] Metastatic pancreatic tumors are rare, accounting for only 2 % of pancreatic malignancies, with colon cancer representing just 1.3 % of these cases. Currently, there is no consensus on the therapeutic approach for secondary pancreatic metastasis from colon cancer.
[PRESENTATION OF CASE] This report details the treatment of an 81-year-old female patient with secondary pancreatic head metastasis from colon cancer. In December 2023, the patient underwent ultrasound-guided percutaneous puncture radioactive Iodine-125 seed implantation radiotherapy. The procedure was successful, with no significant complications. Follow-up at seven months post-procedure showed complete regression of the pancreatic lesion, and the patient remained in good health at nine months.
[DISCUSSION] Colon cancer commonly metastasizes to lymph nodes, liver, lungs, and bones, with pancreatic metastasis being rare. Treatment for pancreatic metastases is complex, but Iodine-125 seed implantation has shown good efficacy for colorectal cancer-related pancreatic metastases. This minimally invasive method offers effective tumor control and recovery.
[CONCLUSION] These findings suggest that Iodine-125 seed implantation is a promising, minimally invasive approach for managing pancreatic metastasis secondary to colorectal cancer, providing effective local control and favorable recovery outcomes.
[PRESENTATION OF CASE] This report details the treatment of an 81-year-old female patient with secondary pancreatic head metastasis from colon cancer. In December 2023, the patient underwent ultrasound-guided percutaneous puncture radioactive Iodine-125 seed implantation radiotherapy. The procedure was successful, with no significant complications. Follow-up at seven months post-procedure showed complete regression of the pancreatic lesion, and the patient remained in good health at nine months.
[DISCUSSION] Colon cancer commonly metastasizes to lymph nodes, liver, lungs, and bones, with pancreatic metastasis being rare. Treatment for pancreatic metastases is complex, but Iodine-125 seed implantation has shown good efficacy for colorectal cancer-related pancreatic metastases. This minimally invasive method offers effective tumor control and recovery.
[CONCLUSION] These findings suggest that Iodine-125 seed implantation is a promising, minimally invasive approach for managing pancreatic metastasis secondary to colorectal cancer, providing effective local control and favorable recovery outcomes.