insight
✂️ 성형 🏥 중증 🌐 전체
← 뒤로

Virological and immunological determinants of hepatitis E virus infection outcomes.

1/5 보강
Current opinion in virology 2025 Vol.73() p. 101491
Retraction 확인
출처
PubMed DOI

Wang X, Bian L, Ha EH, Wang L, O'Shaughnessy K, Zheng Y, Feng Z, Chen WB, Wu X

원문 ↗ DOI ↗ BibTeX ↓ RIS ↓
📝 환자 설명용 한 줄

Hepatitis E virus (HEV) is a leading cause of acute viral hepatitis worldwide, especially in regions with limited sanitation infrastructure.

이 논문을 인용하기

BibTeX ↓ RIS ↓
APA Wang X, Bian L, et al. (2025). Virological and immunological determinants of hepatitis E virus infection outcomes.. Current opinion in virology, 73, 101491. https://doi.org/10.1016/j.coviro.2025.101491
MLA Wang X, et al.. "Virological and immunological determinants of hepatitis E virus infection outcomes.." Current opinion in virology, vol. 73, 2025, pp. 101491.
PMID 40974759
DOI 10.1016/j.coviro.2025.101491

Abstract

Hepatitis E virus (HEV) is a leading cause of acute viral hepatitis worldwide, especially in regions with limited sanitation infrastructure. Unlike hepatitis B virus (HBV) and hepatitis C virus (HCV) - which frequently progress to chronic infections associated with cirrhosis and hepatocellular carcinoma - HEV typically leads to acute and self-resolving infection in immunocompetent individuals. This review explores the mechanistic underpinnings that distinguish HEV's clinical trajectory from HBV and HCV, focusing on viral genome organization, replication strategies, immune evasion tactics, and host immune responses. Understanding these factors provides critical insights into the determinants of viral clearance versus persistence and may guide future vaccine and antiviral development.

MeSH Terms

Hepatitis E; Humans; Hepatitis E virus; Immune Evasion; Virus Replication; Genome, Viral; Animals; Host-Pathogen Interactions

같은 제1저자의 인용 많은 논문 (5)