[Diagnosis and treatment of osteogenic sarcomas, techniques of reconstructions. Future prospects].

Chirurgie; memoires de l'Academie de chirurgie 1994 Vol.120(13) p. 204-15

Poitout D, Tropiano P, Bernat M, Martin G

Abstract

[PATIENTS AND METHODS] We have performed 34 massive bone-cartilage grafts with a follow-up of 2 to 7 years (1988-1993) including 5 complete joint grafts of the knee. Between 1988 and 1993, 8 massive diaphyso-metaphyseal bone grafts were performed. Joint reconstructions using massive bone-cartilage allografts are increasingly used in routine oncology surgery. Long-term rehabilitation and possibilities of immediate anatomic reconstruction of the articular surface, together with mid-term results suggest that the functional results are promising compared with major reconstruction prostheses. Indications for operations are being increasingly widened to younger subjects who have undergone partial or total joint exeresis for tumour. Sleeved prostheses were used for 12 reconstructions (1988-1993) for sarcoma of the knee. RESULTS The risk of sepsis are comparable for the different groups and are mainly related to the quality of the skin repair during chemotherapy. Fractures of the graft occur when the fixation is insufficient or when rehabilitation exercises were too aggressive. Non-consolidation was exceptional when the junction between the allograft and the receiver bone is not surrounded with autologous spongious autografts. Joint instability and arthrosis depend on the stability of the ligament reconstruction. To this day, no Charcot type joint disease has been demonstrated, periarticular innervation has maintained joint trophism.

[DISCUSSION] There are still some incompletely resolved problems concerning the revascularization of the graft, its integration into the skeleton, the outcome of the grafted cartilage and that of the ligament formations attached to the graft or used as allografts. These massive grafts must be studied over a longer period of time but the early results are encouraging. Sleeved grafts using bone-bank specimens could be an intermediary solution which appears to be indicated in cases where the tumoural resection was particularly large removing bone, cartilage, ligaments and muscles. With these sleeved prostheses, the muscles can be refixed onto the graft thus reducing the risk of shank fracture and loosening. The use of a tibial graft with the patellar tendon is helpful in reconstructing the extensor apparatus. However, if rehabilitation is not undertaken rapidly and followed regularly for several months, the graft favours the development of muscular adherances which can be a major limitation to joint mobility.

추출된 의학 개체 (NER)

유형영어 표현한국어 / 풀이UMLS CUI출처등장
해부 bone-cartilage grafts scispacy 1
해부 joint grafts scispacy 1
해부 knee scispacy 1
해부 bone-cartilage allografts scispacy 1
해부 articular surface scispacy 1
해부 skin scispacy 1
해부 graft scispacy 1
해부 bone scispacy 1
해부 spongious autografts scispacy 1
해부 ligament scispacy 1
해부 cartilage scispacy 1
해부 allografts scispacy 1
해부 grafts scispacy 1
해부 tumoural scispacy 1
해부 ligaments scispacy 1
해부 muscles scispacy 1
해부 extensor scispacy 1
해부 muscular scispacy 1
합병증 shank fracture scispacy 1
합병증 patellar tendon scispacy 1
질환 sarcomas C1261473
Sarcoma
scispacy 1
질환 tumour C0027651
Neoplasms
scispacy 1
질환 sarcoma C1261473
Sarcoma
scispacy 1
질환 sepsis C0036690
Septicemia
scispacy 1
질환 Fractures of the graft scispacy 1
질환 arthrosis C0022408
Arthropathy
scispacy 1
질환 Charcot scispacy 1
질환 type joint disease C0022408
Arthropathy
scispacy 1
질환 periarticular innervation scispacy 1
질환 fracture C0016658
Fracture
scispacy 1
질환 allograft scispacy 1
질환 bone-bank specimens scispacy 1
기타 diaphyso-metaphyseal bone grafts scispacy 1
기타 Joint scispacy 1
기타 periarticular scispacy 1

MeSH Terms

Adolescent; Adult; Bone Neoplasms; Bone Transplantation; Cartilage, Articular; Female; Follow-Up Studies; Humans; Male; Orthopedic Fixation Devices; Osteosarcoma; Surgery, Plastic