Changes in peripheral blood B cell levels predict overall survival in patients with advanced liver cancer treated with immune target inhibitors.
1/5 보강
PICO 자동 추출 (휴리스틱, conf 2/4)
유사 논문P · Population 대상 환자/모집단
환자: higher B-cell proportions or absolute counts had significantly longer overall survival (OS) and progression-free survival (PFS)
I · Intervention 중재 / 시술
추출되지 않음
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
Multivariate analysis confirmed elevated B-cell proportion as an independent protective factor for OS. These results suggest that peripheral blood B-cell levels may serve as prognostic biomarkers for PD-1-based immunotherapy in advanced HCC.
PD-1 inhibitors show efficacy in hepatocellular carcinoma (HCC), yet overall outcomes remain poor.
APA
Cheng S, Tang J, et al. (2025). Changes in peripheral blood B cell levels predict overall survival in patients with advanced liver cancer treated with immune target inhibitors.. Discover oncology, 17(1), 79. https://doi.org/10.1007/s12672-025-04236-x
MLA
Cheng S, et al.. "Changes in peripheral blood B cell levels predict overall survival in patients with advanced liver cancer treated with immune target inhibitors.." Discover oncology, vol. 17, no. 1, 2025, pp. 79.
PMID
41364270 ↗
Abstract 한글 요약
PD-1 inhibitors show efficacy in hepatocellular carcinoma (HCC), yet overall outcomes remain poor. In this retrospective study of 258 advanced HCC patients treated between 2019 and 2024, peripheral blood B-cell dynamics were evaluated. Patients with higher B-cell proportions or absolute counts had significantly longer overall survival (OS) and progression-free survival (PFS). Multivariate analysis confirmed elevated B-cell proportion as an independent protective factor for OS. These results suggest that peripheral blood B-cell levels may serve as prognostic biomarkers for PD-1-based immunotherapy in advanced HCC.
🏷️ 키워드 / MeSH 📖 같은 키워드 OA만
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🏷️ 같은 키워드 · 무료전문 — 이 논문 MeSH/keyword 기반
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