A randomized clinical trial of multi-level intervention to improve colorectal cancer screening rates at multiple federally qualified health care centers in New York City.
[INTRODUCTION] Colorectal cancer (CRC) screening rates among patients receiving care at multiple federally qualified health care centers (FQHCs) in New York city are low.
- 연구 설계 randomized controlled trial
APA
Shaukat A, Hu J, et al. (2025). A randomized clinical trial of multi-level intervention to improve colorectal cancer screening rates at multiple federally qualified health care centers in New York City.. Contemporary clinical trials, 159, 108115. https://doi.org/10.1016/j.cct.2025.108115
MLA
Shaukat A, et al.. "A randomized clinical trial of multi-level intervention to improve colorectal cancer screening rates at multiple federally qualified health care centers in New York City.." Contemporary clinical trials, vol. 159, 2025, pp. 108115.
PMID
41326264
Abstract
[INTRODUCTION] Colorectal cancer (CRC) screening rates among patients receiving care at multiple federally qualified health care centers (FQHCs) in New York city are low. Proactive outreach through mailed fecal immunochemical tests (FIT), reminders and navigation are evidence based interventions to improve CRC screening rates but remain untested in this study population.
[OBJECTIVE] To evaluate the effectiveness, implementation, and cost-effectiveness of a multilevel proactive outreach strategy to improve CRC screening rates among underserved adults in Brooklyn, New York.
[METHODS] This is a randomized controlled trial across five FQHCs serving predominantly Black and low-income populations. Adults aged 45-75 who are overdue for CRC screening are randomized to usual care or a multi-level proactive intervention. The intervention includes mailed education and FIT kits, patient navigation, and support for colonoscopy scheduling and follow-up. The primary outcome is CRC screening completion (FIT or colonoscopy) within six months. Secondary outcomes include colonoscopy follow-up after a positive FIT, implementation barriers and facilitators, and cost-effectiveness.
[RESULTS] A total of 1379 participants have been enrolled through May 2025.
[DISCUSSION] This trial addresses a critical gap in CRC prevention by testing a scalable, multilevel outreach model tailored to underserved populations. Findings will inform future strategies to enhance screening rates while reducing screening disparities through sustainable FQHC-based programs.
[OBJECTIVE] To evaluate the effectiveness, implementation, and cost-effectiveness of a multilevel proactive outreach strategy to improve CRC screening rates among underserved adults in Brooklyn, New York.
[METHODS] This is a randomized controlled trial across five FQHCs serving predominantly Black and low-income populations. Adults aged 45-75 who are overdue for CRC screening are randomized to usual care or a multi-level proactive intervention. The intervention includes mailed education and FIT kits, patient navigation, and support for colonoscopy scheduling and follow-up. The primary outcome is CRC screening completion (FIT or colonoscopy) within six months. Secondary outcomes include colonoscopy follow-up after a positive FIT, implementation barriers and facilitators, and cost-effectiveness.
[RESULTS] A total of 1379 participants have been enrolled through May 2025.
[DISCUSSION] This trial addresses a critical gap in CRC prevention by testing a scalable, multilevel outreach model tailored to underserved populations. Findings will inform future strategies to enhance screening rates while reducing screening disparities through sustainable FQHC-based programs.
MeSH Terms
Aged; Female; Humans; Male; Middle Aged; Colonoscopy; Colorectal Neoplasms; Early Detection of Cancer; New York City; Occult Blood; Patient Education as Topic; Patient Navigation; Poverty; Randomized Controlled Trials as Topic; Reminder Systems; Multicenter Studies as Topic; Cost-Effectiveness Analysis
같은 제1저자의 인용 많은 논문 (5)
- Stool Testing for Colon Cancer: Growing Options.
- Colorectal cancer screening test preferences by sociodemographic factors and health beliefs in diverse underserved populations.
- Quality indicators of endoscopists for both index and surveillance colonoscopy are associated with risk of Metachronous Colorectal Neoplasia.
- Correction to: Stool Testing for Colon Cancer: Growing Options.
- Age- and sex-adjusted performance of a colorectal cancer screening test using US census distribution.