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[A Case of Adenocarcinoma Arising from Meckel's Diverticulum with Liver Metastases Diagnosed by CT for Suspected Diverticulitis].

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Gan to kagaku ryoho. Cancer & chemotherapy 📖 저널 OA 0% 2021: 0/1 OA 2022: 0/4 OA 2023: 0/4 OA 2024: 0/44 OA 2025: 0/134 OA 2026: 0/24 OA 2021~2026 2025 Vol.52(13) p. 1074-1076
출처

Sagawa K, Sato N, Iwanaga T, Naito K, Kinoshita K, Yoshikawa K

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A man in his 40s presented with fever and right lower abdominal pain.

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APA Sagawa K, Sato N, et al. (2025). [A Case of Adenocarcinoma Arising from Meckel's Diverticulum with Liver Metastases Diagnosed by CT for Suspected Diverticulitis].. Gan to kagaku ryoho. Cancer & chemotherapy, 52(13), 1074-1076.
MLA Sagawa K, et al.. "[A Case of Adenocarcinoma Arising from Meckel's Diverticulum with Liver Metastases Diagnosed by CT for Suspected Diverticulitis].." Gan to kagaku ryoho. Cancer & chemotherapy, vol. 52, no. 13, 2025, pp. 1074-1076.
PMID 41546252 ↗

Abstract

A man in his 40s presented with fever and right lower abdominal pain. Laboratory data showed elevated inflammatory markers. Abdominal CT showed a 3 cm mass in the mid-lower abdomen with fluid retention and gas continuity with the small bowel, consistent with diverticulitis. Multiple hepatic nodules were also noted. After antibiotic therapy, laparoscopic surgery was performed on hospital day 3. Intraoperatively, a firm mass was found approximately 30 cm proximal to the ileocecal valve, with extensive adhesions to the mesentery and omentum. Multiple white nodules were observed in both hepatic lobes. We performed partial small bowel resection(approximately 60 cm)and partial liver resection for liver biopsy. The pathological diagnosis was adenocarcinoma arising from Meckel's diverticulum with multiple liver metastases(pT3pN1bpM 1a, pStage Ⅳa). We decided to introduce systemic chemotherapy similar to that used for colorectal cancer in small bowel cancer, and we started systemic chemotherapy with mFOLFOX6 at 8 weeks after surgery. Bevacizumab was added from the fourth course due to progressive liver metastasis on CT imaging. After 15 courses, a partial response(PR)of the liver metastases was achieved with no local recurrence or new lesions. Meckel's diverticular adenocarcinoma is extremely rare, and no standard chemotherapy has been established. We have observed relatively good results with mFOLFOX6 plus bevacizumab in this setting.

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