The Blastocystis-colorectal cancer hypothesis: correlation is not causation.
1/5 보강
Although superficially persuasive, claims suggesting a causal link between and colorectal cancer (CRC) lack robust scientific support.
APA
Kurt Ö, Scanlan PD, et al. (2025). The Blastocystis-colorectal cancer hypothesis: correlation is not causation.. Open research Europe, 5, 379. https://doi.org/10.12688/openreseurope.21693.1
MLA
Kurt Ö, et al.. "The Blastocystis-colorectal cancer hypothesis: correlation is not causation.." Open research Europe, vol. 5, 2025, pp. 379.
PMID
41908923 ↗
Abstract 한글 요약
Although superficially persuasive, claims suggesting a causal link between and colorectal cancer (CRC) lack robust scientific support. As is the most common gut protist found in human populations globally, its detection in CRC patients is unsurprising and does not imply pathogenicity. Current claims championing a causal role for in CRC are based on speculative correlations, a single poorly controlled animal study, and inconsistent subtype associations. We argue that linking to CRC is premature, misleading, and may give rise to unnecessary concern in patients that are colonised by or test positive for . We emphasise the need for rigorously designed investigations to establish causal roles for any microorganism in disease and the importance of conclusions being based on solid evidence, particularly in matters of public health.
🏷️ 키워드 / MeSH 📖 같은 키워드 OA만
🏷️ 같은 키워드 · 무료전문 — 이 논문 MeSH/keyword 기반
- Opposing prognostic roles of tumor-associated and circulating MMP8 in colorectal cancer.
- Copper-enriched zinc peroxides induced cuproptosis through concurrent metabolic and oxidative dysregulation for boosting immunotherapy in colorectal cancer.
- Editorial: Altered metabolic traits in gastro-intestinal tract cancers, volume II.
- Macrophage deficiency discordantly regulated tumor growth and metastasis through increased thrombospondin-1 production.
- Time-Resolved Oxygen Dynamics Reveals Redox-Selective Apoptosis Induced by Cold Atmospheric Plasma in HT-29 Colorectal Cancer Cells.
- System-Wide Implementation of Colorectal Cancer Screening in a Value-Based Care Setting.