A report from the Second Tanzania Liver Cancer Conference (TLCC) 2025 - leading the fight against liver cancer in Sub-Saharan Africa.

The Second Tanzania Liver Cancer Conference (TLCC) took place on 25-26 July 2025 in Dar es Salaam, Tanzania with the aim of uniting healthcare providers to continue the fight against liver cancer in Tanzania. The conference focused on the following agenda items: 1) To build awareness among local and international healthcare providers on the status of liver cancer in Tanzania, and the diagnostic and management options afforded to them. 2) To promote a multidisciplinary approach to the clinical care of patients with liver cancer in Tanzania. 3) To foster local and international collaboration in liver cancer research and care. TLCC 2025 was preceded by community-facing pre-conference activities, including hepatitis B virus screening and vaccination, research network symposium and 2 day surgical camp. The conference was attended by 247 healthcare professionals from varying disciplines, featuring 38 local and international speakers who comprehensively covered a wide range of topics related to research and clinical care of liver cancer patients. Overall, the conference was well-received by attendees. As Tanzania's second conference on the subject, TLCC 2025 marked continuing efforts to lead the fight against liver cancer in Sub-Saharan Africa.