An aryl-hydrocarbon receptor-based drug-screening strategy for hepatocellular carcinoma based on dynamic fluorescence imaging.
1/5 보강
The development of fluorescence imaging-based drug-screening methods is crucial.
APA
Sun Y, Li J, et al. (2026). An aryl-hydrocarbon receptor-based drug-screening strategy for hepatocellular carcinoma based on dynamic fluorescence imaging.. Chemical communications (Cambridge, England), 62(9), 2967-2971. https://doi.org/10.1039/d5cc07101a
MLA
Sun Y, et al.. "An aryl-hydrocarbon receptor-based drug-screening strategy for hepatocellular carcinoma based on dynamic fluorescence imaging.." Chemical communications (Cambridge, England), vol. 62, no. 9, 2026, pp. 2967-2971.
PMID
41524493 ↗
Abstract 한글 요약
The development of fluorescence imaging-based drug-screening methods is crucial. We devised an AhR-specific platform AhRPH (LOD = 8.7 ng mL), which consists of vitamin-A functionalized liposomes targeting HSCs and encapsulating AhR-specific probes (ArP). It distinguished drug efficacy: sorafenib/lenvatinib boosted AhR (resistance), and regorafenib suppressed it. This method is specific/sensitive but has limited depth.
🏷️ 키워드 / MeSH 📖 같은 키워드 OA만
같은 제1저자의 인용 많은 논문 (5)
- Construction of hollow double shell NiMn PBA nanozymes for sensitive sarcosine detection a cascade strategy.
- Polydopamine-modified cyclodextrin metal-organic framework for efficient BCL-2 siRNA delivery in lung cancer therapy.
- Nuclear phosphoinositide signaling in cell biology and disease.
- CircNF1 promotes gastric cancer metastasis by stabilizing HMGA2 mRNA through IGF2BP1 interaction.
- Shaping a pro-carcinogenic hepatic microenvironment by TCDD: An integrated approach combining network toxicology, machine learning, molecular docking, molecular dynamics and experimental validation.
🏷️ 같은 키워드 · 무료전문 — 이 논문 MeSH/keyword 기반
- A Phase I Study of Hydroxychloroquine and Suba-Itraconazole in Men with Biochemical Relapse of Prostate Cancer (HITMAN-PC): Dose Escalation Results.
- Self-management of male urinary symptoms: qualitative findings from a primary care trial.
- Clinical and Liquid Biomarkers of 20-Year Prostate Cancer Risk in Men Aged 45 to 70 Years.
- Diagnostic accuracy of Ga-PSMA PET/CT versus multiparametric MRI for preoperative pelvic invasion in the patients with prostate cancer.
- Comprehensive analysis of androgen receptor splice variant target gene expression in prostate cancer.
- Clinical Presentation and Outcomes of Patients Undergoing Surgery for Thyroid Cancer.