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Cytotoxic limonoids from the twigs of .

Journal of Asian natural products research 2026 Vol.28(3) p. 390-396

Yu P, Yang MY, Hu XW, Liu J

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A chemical study on 80% methanol extract of the twigs of led to the isolation of two novel limonoids, paniculatusines A and B ( and ).

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APA Yu P, Yang MY, et al. (2026). Cytotoxic limonoids from the twigs of .. Journal of Asian natural products research, 28(3), 390-396. https://doi.org/10.1080/10286020.2025.2525316
MLA Yu P, et al.. "Cytotoxic limonoids from the twigs of .." Journal of Asian natural products research, vol. 28, no. 3, 2026, pp. 390-396.
PMID 40658497

Abstract

A chemical study on 80% methanol extract of the twigs of led to the isolation of two novel limonoids, paniculatusines A and B ( and ). The structures of the new compounds were elucidated by spectral methods such as 1D and 2D (HMQC, and HMBC) NMR spectroscopy, as well as high resolution mass spectrometry. The isolated limonoids were tested for cytotoxic activities against 5 hepatocellular carcinoma cell lines (SMMC-7721, Bel-7402, MHCC97, HepG2, and Hep3B). Consequently, limonoid exhibited some cytotoxic activities against all the tested tumor cell lines with IC values less than 20 μM.

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