Ageing with cystic fibrosis: Challenges ahead.
1/5 보강
As life expectancy for people with cystic fibrosis continues to improve due to advances in care and CFTR modulator therapies, age-related comorbidities are emerging as new clinical challenges.
APA
Spelier S, van der Wijst MIM, et al. (2026). Ageing with cystic fibrosis: Challenges ahead.. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. https://doi.org/10.1016/j.jcf.2025.12.015
MLA
Spelier S, et al.. "Ageing with cystic fibrosis: Challenges ahead.." Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2026.
PMID
41506936 ↗
Abstract 한글 요약
As life expectancy for people with cystic fibrosis continues to improve due to advances in care and CFTR modulator therapies, age-related comorbidities are emerging as new clinical challenges. This short review summarizes insights from a symposium focusing on ageing and CF at the 20th ECFS Basic Science Conference in March 2025 in Pisa, Italy. Mechanisms of ageing and their involvement in CF disease are first outlined. We then highlight two age-associated comorbidities in CF, cardiovascular disease and colorectal cancer, and outline future research directions to clarify how CF-specific and general ageing mechanisms intersect. Understanding these processes will be crucial for tailoring long-term care strategies in the ageing CF population.
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