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Single-cell integration and multi-modal profiling reveals phenotypes and spatial organization of neutrophils in colorectal cancer.

1/5 보강
Cancer cell 📖 저널 OA 38.1% 2024: 2/4 OA 2025: 7/18 OA 2026: 15/41 OA 2024~2026 2026 Vol.44(1) p. 146-165.e14
Retraction 확인
출처
PubMed DOI

PICO 자동 추출 (휴리스틱, conf 2/4)

유사 논문
P · Population 대상 환자/모집단
670 patient samples and complemented it with single-cell profiles from 266 patients, including cells with low mRNA content, spatial transcriptomics from 3.
I · Intervention 중재 / 시술
추출되지 않음
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
Further, spatial multimodal single-cell profiling reveals niches with IL-1 signaling-based neutrophil-fibroblast interaction. Finally, using an orthotopic mouse model, we show that cancer-derived signals modify neutrophil production in the bone marrow.

Marteau V, Nemati N, Handler K, Raju D, Kirchmair A, Rieder D

PubMed ↗ DOI ↗ BibTeX ↓ RIS ↓

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