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Innovation of a Repeatable Microcatheter-accessible Port (ReMAP): Initial Clinical Results Evaluating Feasibility in the Treatment of Hepatocellular Carcinoma.

Interventional radiology (Higashimatsuyama-shi (Japan) 2026 Vol.11() p. e20250077

Tanaka T, Sato T, Toyoda S, Oshima K, Matsumoto T, Chanoki Y, Shimizu S, Irizato M, Taiji R, Minamiguchi K, Sueyoshi S, Nishiofuku H, Iwamoto H, Itano S

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[PURPOSE] This study aimed to evaluate the feasibility of the Repeatable Microcatheter-accessible Port (ReMAP™) system in initial clinical experiences.

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APA Tanaka T, Sato T, et al. (2026). Innovation of a Repeatable Microcatheter-accessible Port (ReMAP): Initial Clinical Results Evaluating Feasibility in the Treatment of Hepatocellular Carcinoma.. Interventional radiology (Higashimatsuyama-shi (Japan), 11, e20250077. https://doi.org/10.22575/interventionalradiology.2025-0077
MLA Tanaka T, et al.. "Innovation of a Repeatable Microcatheter-accessible Port (ReMAP): Initial Clinical Results Evaluating Feasibility in the Treatment of Hepatocellular Carcinoma.." Interventional radiology (Higashimatsuyama-shi (Japan), vol. 11, 2026, pp. e20250077.
PMID 41878396

Abstract

[PURPOSE] This study aimed to evaluate the feasibility of the Repeatable Microcatheter-accessible Port (ReMAP™) system in initial clinical experiences.

[MATERIAL AND METHODS] Eighteen patients with advanced hepatocellular carcinoma underwent ReMAP™ implantation. The 3.3-Fr catheter tip was positioned in the hepatic, gastroduodenal, or splenic artery, with the side hole located in the common or proper hepatic artery. The 6-Fr proximal end of the catheter was connected to the ReMAP™ device, implanted subcutaneously in the front thigh. A specialized 17-G cannulated needle was used to puncture the ReMAP™ system, allowing insertion of a microcatheter and guidewire, which exited via the side hole and were advanced into the targeted hepatic branches.

[RESULTS] ReMAP™ implantation was successful in all cases. A total of 85 treatment sessions using microcatheters inserted via the ReMAP™ system were performed. All sessions successfully facilitated selective arterial infusion chemotherapy (75 sessions) and selective transarterial chemoembolization (10 sessions). During the treatment period (mean duration: 4.6 months), complications occurred in three cases (18%), including hepatic arterial occlusion, dislocation of the indwelling catheter, and biloma.

[CONCLUSIONS] Locoregional treatments using the ReMAP™ system are feasible for patients with advanced hepatocellular carcinoma.

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