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Integrative metabolomics and network pharmacology reveal the antifibrotic mechanisms of Gurigumu-13 in a rat model of hepatic fibrosis.

1/5 보강
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 📖 저널 OA 15.5% 2022: 0/2 OA 2023: 0/3 OA 2024: 4/7 OA 2025: 7/46 OA 2026: 33/223 OA 2022~2026 2026
Retraction 확인
출처
PubMed DOI

PICO 자동 추출 (휴리스틱, conf 2/4)

유사 논문
P · Population 대상 환자/모집단
추출되지 않음
I · Intervention 중재 / 시술
high, medium, or low doses of Gurigumu-13
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
Its antifibrotic effects are mediated through the modulation of metabolic pathways and interactions with multiple molecular targets involved in inflammation, lipid metabolism, and oxidative stress. By integrating metabolomics with network pharmacology, this work offers novel insights into the mechanisms of Gurigumu-13 and supports its potential clinical application for treating liver fibrosis.

Tong S, Anni, Sudulugeqi, Wang Y, Li X, Du W

PubMed ↗ DOI ↗ BibTeX ↓ RIS ↓

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