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Adjuvant chemo-immunotherapy shows comparable efficacy among mismatch-repair-deficient and mismatch-repair-proficient stage III colon cancer: an exploratory, reconstructed individual patient-level data analysis.

1/5 보강
Journal for immunotherapy of cancer 📖 저널 OA 99.7% 2022: 3/3 OA 2023: 1/1 OA 2024: 13/13 OA 2025: 143/143 OA 2026: 153/154 OA 2022~2026 2026 Vol.14(1)
Retraction 확인
출처
PubMed DOI PMC

PICO 자동 추출 (휴리스틱, conf 2/4)

유사 논문
P · Population 대상 환자/모집단
환자: mismatch-repair-deficient (dMMR) stage III colon cancer; however, its efficacy in mismatch-repair-proficient (pMMR) disease remains unknown
I · Intervention 중재 / 시술
추출되지 않음
C · Comparison 대조 / 비교
추출되지 않음
O · Outcome 결과 / 결론
The interaction test further demonstrated that treatment effect did not differ by MMR status (P=0.808). These findings raise the possibility that adjuvant chemo-immunotherapy may confer benefit even in pMMR stage III colon cancer, which underscores the need for prospective validation in this population.

Chen YT, Wang R, Situ YT, Wang WF, Zhang W, Lin JZ

📖 무료 전문 🟢 PMC 전문 PMC12829358
PubMed ↗ DOI ↗ BibTeX ↓ RIS ↓

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