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Reproducibility and Sex Differences in a STZ-High-Fat Diet Model of MASLD and Early Hepatocarcinogenesis.

2/5 보강

International journal of molecular sciences 📖 저널 OA 100% 2021~2026 2026 Vol.27(7) OA Liver Disease Diagnosis and Treatmen

PICO 자동 추출 (휴리스틱, conf 2/4)

유사 논문

P · Population 대상 환자/모집단

추출되지 않음

I · Intervention 중재 / 시술

streptozotocin to induce T2D-like symptoms followed by a high-fat diet

C · Comparison 대조 / 비교

추출되지 않음

O · Outcome 결과 / 결론

Streptozotocin (STZ) treated mice showed reduced body fat, lower insulin levels, impaired glucose tolerance, and increased expression of genes linked to inflammation, lipid metabolism, and apoptosis. These findings support the STAM model's utility for MASLD research and highlight the importance of sex-specific strategies to limit HCC progression.

OpenAlex 토픽 · Liver Disease Diagnosis and Treatment Diabetes, Cardiovascular Risks, and Lipoproteins Metabolomics and Mass Spectrometry Studies

Hefner M, Hia RA, Nguyen T, Nateqi M, Dhurandhar NV, Hegde V

📖 무료 전문 🟢 PMC 전문 PMC13073077 🔓 OA PDF oa

PubMed ↗ DOI ↗ BibTeX ↓ RIS ↓

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